My boyfriend, Zoloft 100mg (sertraline)

Hi, obviously I can't speak for your boyfriend but this is how I feel.

I have moderate depression and anxiety issues, I am on medication for this and I get very tired quite easily so I just want to 'shut off', even being pleasant can sometimes require a level of energy that I don't have. Even sometimes when I'm scared I just want to be by myself.

I think, it might be good to speak to your boyfriend when he is in a good frame of mind and ask him want he would like you to do when he is feeling particularly out of sorts. Alternatively, if he is being grumpy or mean just accept that he might want a bit of space and, besides, you are right nothing excuses that kind of behaviour. Maybe just say something like you get the sense that he would like some space and to let you know when he's feeling a bit more sociable.

Please note, also, there might be a sense of guilt attached to how he is feeling, I know I'm not always the easiest person to be around and that doesn't feel particularly good.

Sending best wishes to you and your boyfriend.

Hi There.. I am no doctor, but will gladly share my story in the hopes that it might help..

Firstly, how long has he been on? In the beginning there are a few side effects which should be managed.

I was very concerned last week, read hundreds of success stories and hundreds not-so-success..

Let me start by explaining what happens when you start, as this is a bit vague and I found little explanation.... I am no docor, so please excuse the layman terms..

Amongst other chemicals, your brain produces seratonin.. Whatever is not used up gets taken up again - (again, not sure how or when)

So what sertraline does is it blocks this reuptake as it is a SSRI (selective seratonin reuptake inhibitor) So now, there is more seratonin available, but you only have the receptors for it that you had before you started taking sertraline. So your brain goes ahead and makes more receptors to take up all this new seratonin.. This then explains why it takes several weeks to "kick in" you are busy creating receptors.. Also in the meantime, your brain is made aware that there is so much seratonin all of a sudden and halts the production - explaining why we might experience a bad week before things go super...Once again, I apologize, but I explain it like I understand it..

Then the other thing that I found helpful from reading a lot of posts. Sertralin causes insomnia (I am still not sure if it is only in the beginning - I get mixed reaction) so you have to manage this. Take something to improve sleep, but you can't just take any old over-the-counter mediction - it may interfere.

It makes the world of a difference if you had adequate sleep the night before.

Hope it helps..