Posted , 7 users are following.
Just recieved a note from my GP telling me to come in for my 6 monthly Prolia injection.
I've previously raised the possible link between Prolia (denosumab) for osteoporosis and autoimmune disease on this forum. I'm becomming even more convinced it could be likely.
Is it a coincidence I am just starting to feel better than I have since diagnosis 8 months ago?
- Is it the month off work I just had?
- Is my PMR going into remisssion after only 8 months?
- Or could it be that the Prolia is wearing off ?
Is it a coincidence that i only got sick after I had my first Prolia injection?
Side effects of Prolia include (and yes I'm pulling out all the relevant ones):
- back pain
- pain in the arms and legs
- bone, joint and muscle pain
- weakened/impaired immune system
- fatigue
0 likes, 9 replies
margaret22251 FlipDover_Aust
Posted
Before the bone cancer scare i had thats just how i felt.?
for years i used walk one and half miles to work inall weathers, even up to my knees some winters, and nobody could tell me why, only that im was in the change, yes that old story.
Then somebody must have seen the light after my daughter in law suggested they test me for PMR end of story. Have a good day
EileenH margaret22251
Posted
EileenH FlipDover_Aust
Posted
Mind you, there are probably hundreds of drugs for which these are side-effects. Seven days of a statin had me in a far worse state than I'd been in a major PMR flare a couple of months before!
EileenH
Posted
karren61208 EileenH
Posted
My husband who has heart disease has tried most of the statin drugs without success. They all act adversely on his muscles (or does it like PMR act on the soft tissue (fascia)? Because of his experience with shortened muscles, he knows a lot about what to do to recover from these muscle issues which has helped me a lot.
I have to wonder if the duration of time I spent taking osteoporosis drugs isn't what led to my PMR. No one knows what causes PMR, but drugs like Prolia and Forteo mess with the body chemistry. Before osteoporosis, I had no health issues what so ever. I also eat healthy, avoid caffeine, never smoked, exercise regularly. This has been a normal way of living since I was in my early 20's.
MrsO-UK_Surrey FlipDover_Aust
Posted
karren61208 FlipDover_Aust
Posted
Prolia is the last osteoporosis drug I took (after Actonelle and Forteo) before I contracted an osteonecrotic (dead bone) spot in my jaw. This occured in sprint 2014 and I did not show symptoms of PMR until November 2015. I am not on any osteoporosis drugs at this time. I just take calcium and try to walk every day for 40-60 minutes.
The best way to know if you have PMR is to try the prednisone low dose treatment for two weeks (under a good rheumatologist's precise directions) to see if you pains and fatigue go away.
The drugs for osteoporosis can have rare side effects (like osteonecrosis) and your ordinary doctors will not recognize these problems easily. Your best bet is to see a rheumatologist in a teaching / research hospital or center where they and their colleagues see many patients with PMR and rare side effects from osteopororic drugs.
I am also worried that Prolia which interferes with the complete cycle of bone growth and replacement might be building inferior bone mass that might cause additional problems.
As patients, we often do not get the complete picture on these powerful (and risky) drugs.
FlipDover_Aust
Posted
I will be advising my GP that I won't be continuing with the Prolia - and as it is only being administered as a precaution I don't feel the need to replace it with something else. I'm not comfortable with the side effects.
I had an immediate and painful reaction to statins the one time I went on them - not only did my brain turn into mush, but the pain in my legs was incredible. Not doing that again either!
EileenH FlipDover_Aust
Posted
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