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Last throw of the dice maybe

Posted , 6 users are following.

JonWHut
JonWHut

Visited the specialist last week and we are kind of having one last throw of the dice before we consider whether I need to go back in for surgery for a permnament ileostomy...

On the following drugs to see if they will do anything...

A 5 week course of prednisolone (5 wks makes me nervous!)

mebeverine 135mg

metronidazole

and Pentasa 1g sachets

Anyone have any experience of these? I kno wthe metronidazole is a pretty potent antibiotic type drug - absolutely no alcohol and none for 48hrs after I finish the course - I don't drink so it makes no difference to me - but familar with the rest except the Mebeverine...

0 likes, 3 replies

3 Replies

  • ann_and_nick
    ann_and_nick JonWHut

    Posted

    john,

    google clinicaltrials register to see if there are any that are yet recruiting for your disorder...I would travel to Mars for a FMT for CD, UC, or CDI.

    The described meds in combo are a tad crazy or from my perch...I've but one personal experience with flagyl and it cured one type of CDifficle. But with home made yogurts several times a day during treatment. Also took EPA/DHA during the process.

    Should you not find a suitable trial, and go ahead with this cocktail of meds, be sure to supplement heavily with probiotics and psyllium husk and seed as tolerable.

    Wish I had other more benefical advice. Regardless, wish you well, refrain from using basic google, use google scholar or plos one.

  • looloo43
    looloo43 JonWHut

    Posted

    Hi,

    prednisolone were great for me when my colitis flares. mebeverine are often given to ibs sufferers to help with stomach cramp & I believe it is either an anti spasmodic or muscle relaxer specifically for stomach/intestines.they help some people but not everybody. It didn't help me. the metronidazole as you know strong anti biotic often used for intestinal problems. I had these for 2wks at the beginning of my diagnostics for colitis pending tests, they made me feel worse - diarrea, colicky pain & stomach ache - subsequently found no bacteria or infection anyway so didn't have to continue with them. pentasa is a med for colitis which I had before in tablet & suppository forms. quite good, no side effects experienced, but didnt keep me in remission for longer than about 3/4mths, so changed to balsalazide. It looks like they are throwing everything in by the meds you mention to cover ibs, colitis, & possible bacteria or infection. in my experience of all these meds, the worst one was metronidazole it made me feel awful. Have they done a stool test to see if you have any bacteria or infection to see if this med is necessary? I only say this as the other meds in combo may well help you, but the metronidazole may make you feel worse & experience side effects, so you will not know if the the other 3 would benefit you (leaving out the metronidazole I mean). Hope this helps, good luck.

    • JonWHut
      JonWHut looloo43

      Posted

      last metrondiazole today and they haven't made me worst, thankfully. All in all the combination seems to have made a difference. Not running to the toilet as much and the urgency has gone...phew!

      No stool tests done but a chat with the gastro specialist and it feels like lets have a go at sorting this out and see if it works!

       

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