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Omeprazole 40 mg daily

Posted , 3 users are following.

skythroat
skythroat

Hey,

I've chronic gastritis and feel nauseous specially after eating since 9 months! I have really good times tho and the last doc I've met gave me prozac due to anxiety and it destroyed everything. My nausea became harsh and I dropped it.

I'm gonna take omep 40 mg only for gastritis.

My question is about,

Is there any difference between twice a day or once daily?

What do you recommend?

0 likes, 6 replies

6 Replies

  • Barretts
    Barretts skythroat

    Posted

    It is really up to you.

    A paper, "The dose of omeprazole required to achieve adequate intraesophageal acid suppression in patients with gastroesophageal junction specialized intestinal metaplasia and Barrett's esophagus." published August 2013, concluded, "The majority of patients with Barrett's esophagus were controlled with once daily low dose PPI and only a minority required twice daily dosing."

    However some patients feel more comfortable breaking their medication into two doses.

    The best time to take a PPI is half an hour before food. This is because it needs to be absorbed in the duodenum not broken up in the stomach (which is why it is enteric (acid resistent) coated) and the peristalsis of chyme from the stomach will ensure it is pushed there.

    Though the timing isn't critical, it is best to get into the habit of taking them at the same time each day and half an hour beofre breakfast is an easier time to become a habit.

    • skythroat
      skythroat Barretts

      Posted

      I really thank you for your answer.

      Do you think that is any difference between ppi drugs such as rabeprazole vs omeprazole. First doc I've met said me that you can take any ppi, it doesn't matter but the last doc said rabeprazole is better than omeprazole so with only 20 mg rabeprzole a day, you'll notice difference.

      But I've read that many gastritis sufferers take omeprazole for theirs disease. Confused a bit.

    • Barretts
      Barretts skythroat

      Posted

      There's been considerable research comparing the different PPIs which have concluded that all PPIs are as effective as each other when taken in equivalent dose.

      Some patients seem to manage better on one than another though.

      The NHS guidance is lowest effective dose of cheapest effective drug.

      Omeprazole is cheaper than rabeprazole. Those drugs are equivalent weight for weight as well.

      If you want to see an equivalence and costs table and links to the research, visit BarrettsWessex org uk and select Drugs from the dropdown menu of the Treatment tab.

  • bowl
    bowl skythroat

    Posted

    ive been taking losec for 20 years 40mg a day couldnt live without it if i miss one i am in bad burning pains if you need 40 take 40 
    • skythroat
      skythroat bowl

      Posted

      20 mg omeprazole didn't give me a relief. So I want to try 40 mg daily.

      Do you split the doses or take once daily?

  • bowl
    bowl skythroat

    Posted

    i take 20 morning and 20 when going to bed 
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