Reflux oseaghitis can't get it under control
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Hi I have been struggling with bad reflux now for 9 months had endoscopy showed grade 2 scarring 3 months ago still can't get it under control tried lanzoparole and omeprazole to no avail I am now taking esmaprazole for 4 weeks slightly improved but still feel it.To be honest worried about this barretts esoupagaus I suffer from Cfs aswell so think this is contributing in some way.i am awaiting results of barium swallow is there any advice on upping medication not sure if it's going to work to be honest any advice in general thanks
1 like, 12 replies
crissy72393 russ151
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russ151 crissy72393
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Barretts russ151
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Whilst PPIs like lansoprazole, omeprazole etc are excellent for reducing acid, they do nothing to stop reflux.
Barrett's needs reflux + acid + bile to develop. By reducing just one of these elements, you are reducing your risk of developing Barrett's.
However, Non-Erosive Reflux can also cause serious problems. Your CF may well be exacerbated by (even possibly attributable to) aspirated extra-oesophageal reflux (LPR) whic can be responsible for many respiratory disorders including pneumonia and bronchiectasis.
Unfortunately there is no simple drug solution to reduce reflux. If it cannot be managed by lifestyle chages, (lose weight if necessary, avoid tight clothes, avoid exercise that puts pressure on the abdomen after food (including bending), leave at least 3 hours between last meal and going to bed, raise the bedhead by 6 to 8 inches on blocks, sleep on your left side), the alternative is reflux reduction surgery.
russ151 Barretts
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crissy72393 russ151
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Barretts russ151
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Ordinary antacids like Rennie or Tums work instantly on acid already existing.
Alginates like Gaviscon also work by neutralising existing acid while forming a raft floating on stomach contents to reduce reflux and lining the oeosphagus to protect it.
H2 blockers like ranitidine (Zantac) should be taken pre-emptively. They block some of the messages that tell the stomach to make more acid.
PPIs like omeprazole or lansoprazole should be taken every day at the same time (best half an hour before breakfast). They are pre-emptive and their efficacy build up in the sytem over a few days.
crissy72393 Barretts
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Barretts crissy72393
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It's not essential to wait an hour after taking it before eating. The suggestion of half to one hour before food is to ensure it reaches the duodenum to be absorbed there rather than break down in the stomach.
crissy72393 Barretts
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Barretts crissy72393
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The top part of the stomach (fundus) is wrapped arond the base of the oesophagus to enhance the lower oesophageal sphincter and reduce reflux.
My fundoplication 7 years ago was the best thing I ever did. It gave me my life back.
russ151 Barretts
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crissy72393 Barretts
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