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Serotonin Syndrome with Mirtazapine ?

Posted , 3 users are following.

rochan2010
rochan2010

Just wondering if anyone can shed any light on this. I was taking Fluoxetine combined with MIrtazapine and was diagnosed with Serotonin Syndrome. So a few months ago I stopped the Fluoxetine (30 or 40mg) altogether. Now I'm on Mirtazapine (plus Lyrica,Valium,Seroquel,Metoprolol) and have reduced my Mirtazapine from 45 to 30mg. Even since then I keep getting these awful feelings of agitation, can't walk properly, get very mentally confused etc.. Even though I'm not changing my medications, I'm actually getting worse. So I have to come off the Mirtazapine and fortunately have a couple of psychiatrists appointments coming up... Everyone i see just tells me I have anxiety... I can't eat food thats hot otherwise my temperature shoots up, I have migraines that last for hours, go figure.. all the doctors tell me I can't possibly have serotonin syndrome since I'm only taking 30 Mirtazapine and no other serotoninergenic agent.. Not asking for anyone to give me a diagnosis but just wondering if anyone else has had serotonin syndrome or neuro-malignant syndrome on Mirtazapine alone ?

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2 Replies

  • marko6928
    marko6928 rochan2010

    Posted

    I cant really help other than to say dont give in the doctors have knowledge however they do not know everything I personally research my ailments and almost test my doctor to see what he says ( i do this just to make sure i am not being fobbed off with here take a pill and join the queue) If you think you have a problem ask for a second opinion you are intiataled to ask hope this has helped you a little all the best 
  • Fleckers23
    Fleckers23 rochan2010

    Posted

    I know this is a year old, but you may still be wondering.

    I have been taking 15mg Mirtazapine for 4 weeks, over the last week or so I definitely noticed feeling very clumsy and forgetful which then worsedned to mental confusion, antigation and being very short tempered. The best I can describe it as is racing thoughts that are so loud in my head I can't think straight or concentrate. I did some research and realised this sounded like the beginings of serotonin syndrome. I've definitely been experienceing hypomanic episodes too. Sitting in the doctors surgery today I started to shiver and get very emotional and started to have a panic attack. I'm going to take just 7.5mg tonight and for the next few days and see what happens. What happened with you?

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