Local Preparations for Anal Disorders

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There are a number of preparations available for treating symptoms around your bottom (anus). They may be creams, ointments or suppositories. They may help with itching or pain or bleeding. Many conditions cause symptoms in this area. The most common are piles (haemorrhoids), an itchy bottom (pruritus ani), a split in the skin around the bottom (anal fissure) and constipation.

There are quite a lot of medical conditions which can cause symptoms around your bottom and back passage (anus and rectum). For many of these, a local preparation may be helpful. Local preparations are creams, ointments or suppositories which are applied directly to the affected area.

Conditions which may be treated with local preparations include:

Local preparations are applied directly to the area affected. Creams and ointments can be rubbed gently into the sore or itchy area around your bottom (anus). They may come with a nozzle allowing you to insert them into the back passage (rectum), if the problem is further inside.

Suppositories are bullet-shaped tablets which are inserted into the back passage. To use them, make sure you have removed all the plastic or foil wrapping first. It may help to moisten the pointed end with water slightly. Squat down, stand with one foot on a chair or the toilet, or lie down on your side with one knee bent. Push the suppository into the rectum, pointed end first, so that it is completely inside.

Some preparations are available as a rectal foam. This comes in a canister with a nozzle. There will be instructions showing you how to use this.

Enemas are tubes of a substance injected into the bottom. These are usually inserted by a nurse.

Always follow the directions from the pharmacist, your doctor or those in the packet. These will tell you how often and how to apply the preparation you have.

Local preparations for anal disorders fall into the following broad groups. Some may contain a mixture of more than one of the following.

Soothing preparations

There are a wide range of these available. Different ones contain different ingredients. Commonly they contain substances such as bismuth subgallate, zinc oxide or hamamelis. Many are available over the counter. They may soothe soreness or itching and are commonly used for piles (haemorrhoids). Some examples commonly used include:

  • Anusol®
  • Preparation H®
  • Germoloids®

The barrier creams commonly available for nappy rash may also sometimes be helpful to protect a sore area around the bottom at any age. Examples include Metanium® and Sudocrem®.

Steroid preparations

Creams, ointments and suppositories containing steroids are usually mixed with other ingredients. They commonly also contain a soothing preparation and may also contain a local anaesthetic. They are often used for piles. A commonly used one, available both on prescription and over the counter is Anusol HC®. This is a mixture of the soothing preparation Anusol® and the steroid cream hydrocortisone.

Steroids are also available as suppositories and a rectal foam. These are usually used for people with an inflammation of the back passage (proctitis). Examples of steroids used in this way are hydrocortisone, budesonide and prednisolone.

Preparations containing local anaesthetics

Local anaesthetics numb the skin, and help for conditions that are painful. They may be mixed with a soothing preparation and a steroid preparation for piles. An example of this is Anugesic HC®. This is a mixture of a local anaesthetic with the soothing preparation Anusol® and the steroid cream hydrocortisone. They may also be used to numb the pain of a split in the skin of the anus (anal fissure). Sometimes they are also used for children who have constipation. Young children sometimes try to stop their poo (stools) coming out when they are constipated. This is because large hard stools are painful to pass. An anaesthetic cream makes it less painful, so they are able to pass the stools.

Lidocaine is a common anaesthetic used in these creams. Others are tetracaine, cinchocaine, and pramocaine.

Preparations containing local anaesthetics should not be used for more than a few days. They should be applied sparingly. Pay careful attention to the instructions.

Topical nitrates

Nitrates are medicines which open up blood vessels, allowing more blood to flow. A nitrate cream is used for anal fissures. The extra blood flow helps them to heal. The topical glyceryl trinitrate cream Rectogesic® is used for this. It may cause headaches in some people as a side-effect.

Another medicine which works in a similar way is diltiazem cream. This is not currently licensed for anal fissures but specialists may use it for this. The National Institute for Health and Care Excellence (NICE) has examined the evidence on its use. Diltiazem cream seems effective and less likely to cause headaches than glyceryl trinitrate.

Suppositories for constipation

Glycerol suppositories are one of the options used for constipation. You put them into your bottom, and they usually stimulate a bowel movement shortly afterwards. They are effective when you have stool which is stuck at the end of your bowel, near or in your back passage. Bisacodyl is another suppository used for constipation.

Other local preparations for anal disorders

The above are the most commonly used preparations. However, other treatments which may be applied directly to the bottom area include:

  • Antifungal creams for thrush infections
  • Podophyllotoxin for anogenital warts. Imiquimod is another cream which may be used for warts.
  • Moisturising (emollient) creams for dry skin or mild eczema in this area.
  • Botox® injections are occasionally used by specialists to treat anal fissures which are not getting better.
  • Phenol is an injection sometimes used by specialists to shrink piles.

Some preparations mentioned above are available from a pharmacy or supermarket. Many soothing preparations and some containing steroids are available over the counter without a prescription. For others, such as nitrate ointment, or local anaesthetic preparations, you may need a prescription from your doctor.

If you are using a local preparation for a problem around your bottom and it is not improving, make an appointment to see your doctor. If you have any bleeding from your bottom, see your doctor to be checked for the cause.

Most local preparations for anal disorders do not commonly have side-effects. However, always read the leaflet that comes with your preparation. Using these preparations too liberally or for too long may cause problems. Local anaesthetic creams may cause the skin to be too sensitive if used for more than a few days. If too much is used, they may cause problems elsewhere in your body, such as affecting your heart rate. Using a steroid cream for too long may cause thinning of the skin in that area in some cases. Nitrate creams may cause a headache as a side-effect.

Some people may be sensitive to an ingredient in any cream or ointment. If a rash or itching develops in an area where you have applied a local preparation then stop using it immediately.

Always use the preparation as advised by your doctor or pharmacist.

Original Author:
Dr Mary Harding
Current Version:
Peer Reviewer:
Dr Hayley Willacy
Document ID:
29315 (v1)
Last Checked:
Next Review:
The Information Standard - certified member
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