Immunisation - Usual UK Schedule

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This leaflet provides information about the normal immunisation schedule for people in the UK.

UK 2016 Immunisation Schedule

AGE
Immunisation (Vaccine Given)
2 months
  • DTaP/IPV(polio)/Hib (diphtheria, tetanus, pertussis (whooping cough), polio, and Haemophilus influenzae type b) - 5-in-one injection (Pediacel® or Infanrix IPV Hib®); plus:
  • PCV (pneumococcal conjugate vaccine) - in a separate injection (Prevenar 13®).
  • Rotavirus (Rotarix®) - oral route (drops).
  • Meningitis B (Bexsero®).
3 months
  • DTaP/IPV(polio)/Hib 5-in-one injection, 2nd dose (Pediacel® or Infanrix IPV Hib®); plus:
  • Rotavirus (Rotarix®) - oral route (drops).
4 months
  • DTaP/IPV(polio)/Hib 5-in-one injection, 3rd dose (Pediacel® or Infanrix IPV Hib®); plus:
  • PCV 2nd dose (Prevenar 13®) - in a separate injection.
  • Meningitis B 2nd dose (Bexsero®).
Between 12 and 13 months
  • Hib/MenC (combined as one injection) - 4th dose of Hib and 1st dose of MenC (Menitorix®); plus:
  • MMR (measles, mumps and rubella) - combined as one injection (Priorix® or M-M-RVAXPRO®); plus:
  • PCV 3rd dose (Prevenar 13®) - in a separate injection.
  • Meningitis B 3rd dose (Bexsero®).
2-7 years
  • Nasal flu spray annually (Fluenz®). For children aged 2, 3 and 4, this is usually given in the GP surgery. Children in school years 1, 2 and 3 may have this at school.
3 years and four months
  • Preschool booster of DTaP/IPV(polio). 4-in-one injection (Repevax® or Infanrix-IPV®); plus:
  • MMR 2nd dose (Priorix® or M-M-RVAXPRO®) - in a separate injection.
12-13 years (girls)
  • HPV (human papillomavirus types 16 and 18) - two injections (Gardasil®). The second injection is given 6-12 months after the first one.
14 years
  • Td/IPV(polio) booster. 3-in-one injection (Revaxis®).
  • Men ACWY: combined protection against meningitis A, C, W and Y (Nimenrix® or Menveo®).
Adults
  • Influenza (annual) and PPV (pneumococcal polysaccharide vaccine): for those aged over 65 years and also those in high-risk groups.
  • Td/IPV(polio): for those not fully immunised as a child (Revaxis®).
  • DTaP: for pregnant women from 20 weeks of gestation to protect the newborn baby against whooping cough (Boostrix®).
  • Shingles (Zostavax®) vaccine: for adults aged 70 years. (Plus catch-up for adults aged 78 and 79.)

Notes:

  • Diphtheria, tetanus, pertussis (whooping cough), polio and Hib are combined into one 5-in-one injection - the DTaP/IPV(polio)/Hib vaccine.
    • Without Hib, the 4-in-one injection combines diphtheria, tetanus, pertussis and polio - the DTaP/IPV(polio) vaccine. This is the one given as a preschool booster.
    • Without Hib or polio, the 3-in-one injection combines diphtheria, tetanus and pertussis - the DTaP vaccine. This is given to pregnant women.
    • Without Hib or pertussis, and using a low-dose diphtheria, the Td/IPV(polio) vaccine is the other variation of three of these vaccines in one. This is given where a tetanus booster is needed.
  • Five doses of the combined diphtheria, tetanus and polio vaccine are enough to provide long-term protection through adulthood; however:
    • A DTaP booster is currently offered to pregnant women from 20 weeks of gestation (started September 2012). This aims to counter the rise in whooping cough in newborn babies.
    • Tetanus boosters may be advised if travelling to a high-risk area, or after a high-risk wound if the last booster was more than ten years previously. This is given in the 3-in-one Td/IPV(polio) (tetanus, low-dose diphtheria and polio) vaccine (Revaxis®).
  • Meningitis C (MenC) vaccine is combined with Hib for one injection to give the first dose. The second dose is given in the combined Men ACWY vaccine, protecting against the A, C and Y types of meningitis as well as meningitis C.
  • Polio immunisation changed in 2004. The polio vaccine is now combined with DTaP/Hib or Td and given by injection. It used to be given by mouth (oral vaccine) as a few drops of vaccine on the tongue.
  • Measles, mumps and rubella vaccines are combined into one injection - MMR.
  • The UK immunisation schedule constantly changes. Some of the newer vaccines include:
    • Immunisation against human papillomavirus (HPV), which was introduced in the UK for girls in 2008.
    • Rotavirus vaccination, which started in the UK in July 2013.
    • Nasal flu vaccine, which began in 2013 in children aged 2-4 years, and has recently been extended to children in school years 1, 2 and 3.
    • Meningitis B vaccine and meningitis ACWY vaccine, which were introduced in 2015.

There are leaflets available with more information about some of the vaccines listed in the schedule above. There are also some leaflets available for the specific brands of vaccine given.

The body is given a vaccine which is a small dose of an inactive form of a germ (bacterium or virus), or a poison (toxin) made by the germ. As it is inactive, it does not cause infection. However, the body makes antibodies and/or white blood cells (immune cells) against the germ or toxin. Antibodies are proteins in the bloodstream that attack infecting germs. Once we are immunised, the antibodies and/or immune cells are ready to attack the germ if it begins to invade our body. More antibody can quickly be made from cells which have previously made the particular antibody.

For some bacteria and viruses it has been difficult to produce a vaccine; however, technology is advancing and new vaccines will be available in the future.

A newborn baby has passive immunity to several diseases, such as measles, mumps and rubella (MMR), from antibodies passed from its mother via the placenta. This passive immunity of babies usually only lasts for a few weeks or months but, for MMR, it lasts up to one year. Immunisation with vaccines is called active immunity and provides long-term immunity.

Immunisation has caused dramatic improvements in health; diphtheria, tetanus, whooping cough (pertussis), measles and polio are now rare in many countries. Vaccination resulted in smallpox being eradicated from the world. It is hoped the same will soon be true for polio. Even some of the less serious illnesses for which there are vaccines can have life-threatening complications in some people. Immunisation saves countless lives. Some immunisations are offered to all people through the childhood immunisation programme. Some are offered to at-risk groups - listed below.

If the usual schedule is interrupted or delayed for any reason, it can be resumed at any time. There is no need to start again. However, it is best to have the immunisations at the correct time, as the earlier the child is protected, the better. Some exceptions to this rule are:

  • Whooping cough (pertussis) vaccine is not usually given to children over the age of 7 years.
  • Hib vaccine. If the child is aged over 13 months but under 4 years and has not had any previous doses, only one dose is needed. Hib is not given to children aged over 4 years, as the risk of infection from this germ (bacterium) is much less than in young children and babies.
  • Pneumococcal conjugate vaccine (PCV): If a child between the ages of 1 and 2 years has not had any previous dose of PCV, or only had one previous dose, a single dose of PCV should be given. Children aged over 2 years and who are not in an at-risk group do not need to be immunised.
  • Rotavirus vaccine: babies should only receive the first dose of the rotavirus vaccine if they are younger than 15 weeks of age.

Diphtheria is caused by the germ (bacterium) Corynebacterium diphtheriae. It causes a serious throat and chest infection. Since immunisation was started in the 1950s, diphtheria has now become rare in the UK.

Haemophilus influenzae type b (Hib) is a bacterium which can cause pneumonia and meningitis. Children under the age of 4 years are most at risk. Before the introduction of the vaccine in 1992, 1 in 600 children developed some form of Hib disease before their fifth birthday. It is now rare.

Measles is caused by the measles virus. It causes a miserable feverish illness with a rash. Complications occur in some cases, such as pneumonia, convulsions or brain inflammation (encephalitis). Before the introduction of a measles vaccine in 1968, measles was a common childhood illness. It is now rare in the UK, although the incidence of measles is increasing in some areas, due to some children not being immunised.

Mumps is caused by the mumps virus. The infection typically causes inflammation and swelling of the salivary glands. Complications occur in some cases, such as pancreatitis, inflammation of the testes (orchitis), meningitis, and inflammation of the brain (encephalitis). Mumps may cause permanent deafness in one ear. Again, mumps is now rare in the UK due to immunisation.

Rotavirus is an infection from a virus. It causes sickness (vomiting) and diarrhoea. In most cases the infection clears within a few days; however, it sometimes takes longer. It is easily spread from an infected person to another by close contact. Outbreaks of rotavirus that affect many people can occur - for example, in nurseries or schools. Before the vaccination, there were thought to be about 130,000 cases each year in England and Wales. Around 18,000 children are thought to be admitted to hospital each year because of rotavirus infection. Since the vaccine, there is only about one third of this number of cases.

Rubella (German measles) is caused by the rubella virus. It causes a mild illness with a rash. However, if a pregnant woman has rubella, the virus is likely to cause serious damage to the unborn child. The child is likely to be born with multiple defects (congenital rubella syndrome). The aim of rubella immunisation is to eliminate the rubella virus from the community as much as possible. Since rubella immunisation was introduced in 1970 there has been a dramatic fall in the number of babies born with the congenital rubella syndrome.

Meningococcal meningitis. Meningococcal bacteria are one cause of meningitis and severe blood poisoning (sepsis). There are many types of meningococcus but cases of meningitis and septicaemia caused by group C have fallen since immunisation was introduced. It is hoped that now children and young people are also immunised against groups B, A, W and Y, cases will become more and more uncommon.

Whooping cough (pertussis) is caused by a bacterium called Bordetella pertussis. This causes a prolonged and distressing cough. Some infected children develop complications such as pneumonia or brain damage. There used to be regular epidemics of whooping cough in the UK before immunisation became available. It had become uncommon in the UK; however, over the past few years there have been more cases. The worst complications were noted to be in very young babies, who had not completed their immunisation courses. This is why in the UK pregnant women are currently vaccinated during pregnancy, so they can pass their immunity on to their new babies and keep them safe from this illness.

Pneumococcus is a bacterium which can cause pneumonia, meningitis and some other infections. Pneumococcal infection can affect anybody. However, young children, people aged 65 and over, and some other groups of people are at increased risk of pneumococcal infection.

Polio (poliomyelitis) is an illness caused by the polio virus. The virus first infects the gut but then travels to the nervous system and can cause a meningitis-like illness. This may damage some nerves. This may lead to wasting of muscles and sometimes paralysis of one or more of the limbs. The illness can seriously affect breathing in some people and may even lead to death.

Tetanus is an infection caused by a bacterium called Clostridium tetani which is found in the soil. It causes severe and agonising muscle contractions and is often fatal. Due to immunisation, it is very uncommon in the UK.

Human papillomavirus (HPV) is a virus that can affect the skin and mucosa (the moist membranes lining different parts of the body, including the mouth, throat and genital area). There are over one hundred different types of HPV and about 40 of these can affect the genital area. They can cause genital warts. Two types, HPV 16 and 18, are involved in the development of most of the cases of cancer of the womb (cervix). The HPV vaccine is very effective at stopping cancer of the cervix from developing.

Shingles is a condition where the chickenpox virus is reactivated in just one area of skin. It causes pain and a rash and can make people feel very down and unwell.

Influenza (flu) is due to an infection with one of the influenza viruses. It typically cause a high temperature (fever), aches and pains in muscles and joints, a cough and various other symptoms. Most people recover fully but complications such as pneumonia can sometimes develop. Complications are sometimes serious. Every year some people die from the complications of flu. Certain groups of people are more at risk of complications, particularly the elderly, the very young, and pregnant women.

If you travel abroad

If you travel abroad it is recommended that you should be protected against the local infections if immunisations are available. Ideally, see your practice nurse or GP for advice on travel at least two months prior to your departure. Doctors and nurses are regularly updated with immunisation requirements for every country in the world.

The flu jab (seasonal influenza immunisation)

Seasonal influenza is the strain of influenza virus that arrives in the UK each autumn. The actual strain varies from year to year and a new immunisation is developed each year to protect against the prevailing strain. The current influenza injectable vaccines contain two different types of influenza A and one type of influenza B virus.

The aim is to protect people who are more likely to develop complications from flu. You should be immunised against flu each autumn if you are aged 65 or over. Children aged 2-7 are now immunised each year. Also, people of any age in any of the following at-risk groups. If you:

  • Have any ongoing (chronic) lung diseases. Examples include chronic bronchitis, emphysema, cystic fibrosis and severe asthma (needing regular steroid inhalers or tablets). It is also recommended for any child who has previously been admitted to hospital with a chest infection.
  • Have a chronic heart disease. Examples include angina, heart failure or if you have ever had a heart attack.
  • Have a serious kidney disease. Examples include nephrotic syndrome, end-stage chronic kidney disease, a kidney transplant.
  • Have a serious liver disease such as cirrhosis.
  • Have diabetes.
  • Have a poor immune system. Examples include if you are receiving chemotherapy or steroid treatment (for more than a month), if you have HIV/AIDS or if you have had your spleen removed.
  • Have certain serious diseases of the nervous system, such as multiple sclerosis, or have had a stroke in the past.
  • Live in a nursing home or other long-stay residential care accommodation. 

In addition to the main at-risk groups of people listed above:

  • You should be immunised if you are the main carer for an elderly or disabled person whose welfare may be at risk if you fall ill with influenza.
  • Staff involved in direct patient care may be offered a flu jab from their employer.
  • Pregnant women - even if otherwise healthy. It is now recommended that all pregnant women receive the influenza immunisation.

Pneumococcal immunisation

Pneumococcus is a germ (bacterium) that can cause pneumonia and meningitis. Immunisation against pneumococcus with the pneumococcal conjugate vaccine (PCV) became part of the routine childhood immunisation programme in the summer of 2006.

In addition, people who are at increased risk of infection with this bacterium should be immunised. For children aged under 5 years this is with the (routine) PCV plus a one-off dose of pneumococcal polysaccharide vaccine (PPV) as soon as possible after the second birthday. For people aged over 5 years, it is with a one-off dose of PPV.

You are at increased risk, and should be immunised, if you:

  • Are aged 65 or over.
  • Do not have a spleen or if your spleen does not work properly.
  • Have an ongoing (chronic) serious lung disease. Examples include chronic bronchitis, emphysema and cystic fibrosis. It is only recommended for those with very severe asthma who need frequent courses of steroid tablets.
  • Are a child who has previously been admitted to hospital with pneumonia.
  • Have a chronic heart disease. Examples include congenital heart disease, angina, heart failure or if you have ever had a heart attack.
  • Have a serious chronic kidney disease. Examples include nephrotic syndrome, kidney failure or if you have had a kidney transplant.
  • Have a chronic liver disease such as cirrhosis or chronic hepatitis.
  • Have diabetes which requires insulin or tablets to control it.
  • Have a poor immune system. Examples include if you are receiving chemotherapy or steroid treatment (for more than a month), if you have HIV/AIDS or if you have previously had your spleen removed.
  • Have a cochlear implant.
  • Have a cerebrospinal fluid (CSF) shunt (a shunt to drain the fluid that surrounds the brain).

Immunisation against tuberculosis (TB) - the BCG vaccine

The BCG vaccine (BCG stands for bacillus Calmette-Guérin) is offered to the following people in the UK:

  • All infants (0-12 months old) living in areas of the UK where there is a high rate of TB. That is, areas where the incidence of TB is 40 cases per 100,000 people per year or greater.
  • Infants whose parents or grandparents were born in a country with a high rate of TB. That is, countries where the incidence of TB is 40 cases per 100,000 people per year or greater.
  • The following groups of people who have not previously been immunised:
    • Children (aged under 16 years) who have come to live in the UK from countries where TB is common (at least 40 cases per 100,000 people per year).
    • Children between the ages of 6-16 years who have a parent or grandparent who was born in a country where the incidence of TB is 40 cases per 100,000 people per year or greater.
    • Children aged under 16 years who are close contacts of an individual who has active TB affecting their lungs.
    • Children aged under 16 years who were born in, or have lived for more than three months in, a country where the incidence of TB is 40 cases per 100,000 people per year or greater.
    • People at an increased risk due to their job - for example, health workers, prison staff, etc.

Note: until 2005, all schoolchildren in the UK were routinely given the BCG vaccine at about the age of 13 years. The policy changed in autumn 2005 and those now immunised are in the groups listed above. The policy change was due to the changing patterns of TB in the UK.

Rates of the disease are now very low in many parts of the country and children living in these areas have a very low risk of infection. However, in other areas, rates of TB are increasing. This is why the BCG vaccine is now mainly targeted at babies living in areas where there is an increasing rate of TB cases. Your doctor or midwife will be able to tell you if you live in an area with a high rate of TB. If your baby is born in a higher-risk area, you will be offered a BCG vaccine for the baby soon after birth.

Hepatitis B immunisation

This is advised for people who are at increased risk of contracting hepatitis B - for example:

  • Workers who are likely to come into contact with blood products, or are at increased risk of needlestick injuries, assault, etc. For example, nurses, doctors, dentists, medical laboratory workers, prison wardens, etc. Also, staff at residential centres where there is a risk of scratching or biting by residents.
  • People who inject street drugs, and the sexual partners and children of those people.
  • People who change sexual partners frequently.
  • People who live in close contact with someone infected with hepatitis B. (You cannot catch hepatitis B from touching people or normal social contact. However, close regular contacts are best immunised.)
  • People who regularly receive blood transfusions (for example, for haemophilia).
  • People with certain kidney or liver diseases.
  • People who live in residential accommodation for those with learning difficulties. People who attend day centres for people with learning difficulties may also be offered immunisation.
  • Families adopting children from countries with a high or intermediate prevalence of hepatitis B when the hepatitis B status of the child is unknown. (It is, however, advisable for the child to be tested for hepatitis B.)
  • Foster carers or if you live with foster children.
  • Prison inmates.
  • Travellers to countries where hepatitis B is common, who place themselves at risk when abroad. The risk behaviour includes sexual activity, injecting drug use, undertaking relief work and/or participating in contact sports. Also, if you may need a medical or dental procedure in these countries and the procedure may not be done with sterile equipment.
  • Babies who are born to infected mothers.

Immunisation against chickenpox (varicella)

A vaccine is offered to healthcare workers (doctors, nurses, etc) who have not previously had chickenpox and so are not immune and may catch chickenpox. (About 1 adult in 10 has not had chickenpox as a child.) If you are not sure if you have had chickenpox then a blood test can check if you have previously had it.

The aim is to protect healthcare workers from developing chickenpox, but also patients. If chickenpox does not occur in any healthcare staff, this protects patients with a poor immune system (such as people with leukaemia) who may catch chickenpox from a healthcare worker who may be developing a chickenpox infection without realising it.

Close contacts of people with a poor immune system who are not immune to chickenpox should also have this immunisation. For example, brothers and sisters of a child with leukaemia who have not previously had chickenpox. Infection with chickenpox can be very serious for people with a poor immune system.

The vaccine is also sometimes given to patients who may develop a weakened immune system in the future. For example, those who are likely to need high doses of steroid tablets. Your doctor will be able to give more information about this. 

Other situations

In some special circumstances other immunisations are considered. For example, workers who handle animals may be offered rabies immunisation. Those in close contact with people who have certain forms of meningitis may be offered specific immunisations. Discuss with your doctor or practice nurse if you think you fall into one of these groups.

Some adults are not fully immunised against polio and tetanus. These immunisations were first introduced into the UK in the late 1950s. If you were born before then you might not have received full protection from these illnesses. Your practice nurse will be able to advise you if you are unsure.

There are very few reasons why people should not receive their full course of immunisations. Immunisations are generally very safe and effective. The main reasons for a person not to have a vaccine is if they have had a severe allergic reaction to a previous dose of that vaccine or to an ingredient in the vaccine that was also present in a different vaccine. People who have had very severe allergic reactions to egg should not have the yellow fever or flu vaccines other than under specialist care. This is because there may be small amounts of egg protein in these vaccines.

Certain vaccines (for example, the BCG vaccine) are not usually given to women who are pregnant. They may not be suitable for people whose immune systems are not working very well (people who are immunosuppressed.)

If you are unwell with a high temperature (fever), vaccination is usually put off until you are well again.

See the separate leaflets on individual immunisations for more details.

Information on immunisation from NHS Choices

Web: www.nhs.uk/Planners/vaccinations/Pages/Vaccinationchecklist.aspx

Original Author:
Dr Tim Kenny
Current Version:
Peer Reviewer:
Prof Cathy Jackson
Document ID:
4275 (v47)
Last Checked:
28/09/2016
Next Review:
28/09/2019
The Information Standard - certified member
Now read about Immunisation Schedule (UK)

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