Dihydrotachysterol (AT 10)

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Dihydrotachysterol is a type of vitamin D.

Make sure you understand how much to take and when to take it.

You will need to have regular blood tests while you are taking this medicine so that your doctor can make sure the dose is right for you.

Make sure you know the symptoms of too much calcium in your blood - these are losing your appetite, feeling thirsty, being sick, feeling tired, and losing weight. See your doctor if you develop these symptoms.

Type of medicineA type of vitamin D
Used forLow blood calcium levels due to hypoparathyroidism
Also calledAT 10®
Available asOral solution (drops)

Dihydrotachysterol is a form of vitamin D. Vitamin D helps you to absorb calcium from what you eat. You need calcium to keep your bones strong, and to help your muscles and nerves work properly. If you have a low level of calcium in your blood, it can cause a number of different symptoms, including muscle cramps, pain and twitching. Low levels of calcium can be caused by a problem with your parathyroid glands, called hypoparathyroidism. Dihydrotachysterol is used to treat low blood levels of calcium when this is caused by hypoparathyroidism.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking dihydrotachysterol it is important that your doctor knows:

  • If you are allergic to peanuts or soya. If so, you must not take this medicine.
  • If you are pregnant or breast-feeding.
  • If you have sarcoidosis. This is a condition causing inflammation, particularly in your lungs and lymph system. Sarcoidosis may make you more sensitive to dihydrotachysterol than normal.
  • If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • If you have ever had an allergic reaction to a medicine.
  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The leaflet will give you more information about dihydrotachysterol and a full list of side-effects which you may experience from taking it.
  • Take dihydrotachysterol exactly as your doctor tells you to. It is likely you will be asked to take 3-5 ml for the first three days, and then your dose will be adjusted depending on the results of a blood test. You could then be asked to take a dose each day, on alternate days, or several times a week. Your doctor will tell you what is right for you, and how much to take for each of your doses. You can take dihydrotachysterol before or after meals.
  • Make sure you understand how to measure out your doses using the dropper. You can ask your doctor, nurse or pharmacist to explain this to you again if you are uncertain.
  • If you forget to take a dose, take it as soon as you remember (unless it is time for your next dose, in which case leave out the missed dose). Do not take two doses together to make up for a forgotten dose.
  • Keep your regular doctor's appointment so your progress can be monitored. You will need to have regular blood tests while you are taking this medicine to make sure that the dose you are taking is correct for you.
  • You should consider wearing a MedicAlert® bracelet (or similar), or carry some kind of ID with you, to identify yourself as having hypoparathyroidism. This is so that if you collapse, are confused or are injured, doctors will know that you need prompt treatment with calcium.
  • Eating foods rich in vitamin D and calcium may help, such as oily fish (sardine, herring, salmon and tuna), liver, dairy products and eggs.
  • If you buy any medicines, check with a pharmacist that they are suitable for you to take with dihydrotachysterol.
  • Treatment with dihydrotachysterol is usually long-term. Continue to take it regularly unless you are advised otherwise by your doctor.
  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking dihydrotachysterol.

Along with their useful effects, medicines can cause unwanted side-effects although not everyone experiences them. Any side-effects caused by dihydrotachysterol are likely to be due to too much calcium in your blood, which means that your dose will need adjusting. The first signs of too much calcium are loss of appetite, tiredness, and feeling sick. This could then lead to being sick, stomach cramps, feeling thirsty, urinary frequency, dizziness, and headache. If you experience these symptoms, it is important that you make an appointment to see your doctor straightaway.

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.

This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.

Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.

If you have any questions about this medicine ask your pharmacist.

Further reading & references

  • Manufacturer's PIL, AT10®; Intrapharm Laboratories Ltd, The electronic Medicines Compendium. Dated February 2013.
  • British National Formulary; 65th Edition (Mar 2013) British Medical Association and Royal Pharmaceutical Society of Great Britain, London

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.

Original Author:
Helen Allen
Current Version:
Peer Reviewer:
Dr John Cox
Document ID:
3635 (v23)
Last Checked:
Next Review:
The Information Standard - certified member

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