Damaged arteries can be treated with nanoparticles

A US Study has shown that the harmful plaques found in the walls of arteries, which often lead to heart attacks and strokes, could potentially be treated using nanoparticles.1

The research was carried out by several US universities, and used mice affected by atherosclerosis, the process that leads to the build-up of plaques in artery walls.

The researchers identified a protein called annexin A1, which is released by the body when it attempts to repair these plaques and covered a section of this protein with a special type of nanoparticle. This was then used to aid the plaque repair with promising results.

Researchers have now planned tests on pigs and primates, and if these are successful they are likely to follow up with human trials.

In the meantime, the best way to avoid atherosclerosis is of course to have a healthy lifestyle, including maintaining a healthy weight, not smoking and getting plenty of exercise.


1 Fredman G, Kamaly N, Spolitu S, et al. Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice. Science Translational Medicine. Published online February 18 2015

News sources:

Drones could be used to seek out arteries to prevent heart attacks. The Daily Telegraph, February 18 2015

Nano drones mend arteries: Microscopic particles that seek out and repair damage could be future of treatment for heart disease and strokes. Mail Online, February 19 2015

Microscopic DRONES could be used to treat heart and stroke patients in the future. Daily Mirror, February 18 2015


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