Steroids and their side effects

The recent controversy over Russian athletes and Olympic doping have brought the issue of performance-enhancing drugs into the headlines again. And as usual, steroids are in the frame. Steroids have had a bad press over the years - a combination of their side effects and misuse of anabolic steroids by bodybuilders. But we actually make steroids in our own bodies - and used as your doctor recommends, they can be effective and safe.

The steroids used in medicine are almost all 'corticosteroids' - made in your body, these act as hormones or chemical messengers. They have a role in your immune system, affecting inflammation in the body. They're prescribed in tablet, inhaler, cream/ointment and injection form for different medical conditions. Mostly they're used to reduce inflammation which is causing problems in the body.

Steroid tablets are used to treat serious allergic reactions like life-threatening anaphylaxis. They may be given in short courses for severe flare-ups of conditions like asthmachronic obstructive pulmonary disease (COPD) and hives (urticarial). They're also prescribed for auto-immune conditions, where the body's immune system has turned on itself and is attacking part of the body. This includes Lupusinflammatory bowel diseaserheumatoid arthritis and multiple sclerosis.

Polymyalgia rheumatica causes painful muscles, especially in your upper arms and thighs. Giant Cell Arteritis is caused by inflammation of the blood vessels in your temples, giving rise to pain and soreness around the temples and sometimes loss of vision. These are both treated with steroid tablets, usually for a couple of years. Your doctor can monitor your response with a blood test called an ESR.

Steroid injections are often given directly into inflamed joints to reduce pain, swelling and stiffness. This can cause temporary pain, so they're often injected along with a local anaesthetic.

Inhaled steroids come in a wide variety of inhaler devices, and are used mainly to treat asthma and COPD. They're called 'preventer' inhalers - they don't relieve wheezing or breathlessness in the short term, like 'reliever' inhalers, but they damp down inflammation if you use them regularly. This helps reduce symptoms and flare-ups which can land you in hospital. Unless your symptoms settle naturally (this can happen with asthma) you'll need to take them regularly in the long term.

Because inhaled steroids are delivered straight to the lungs, where they're needed, the dose you take is tiny compared to that in steroid tablets. That means they don't have many side effects - although they can cause a sore mouth if you don't rinse your mouth out after using them. There is some suggestion that high-dose inhaled steroids can increase your risk of pneumonia if you have COPD. Your doctor can advise you on the safest type for you.

Steroid creams and ointments come in many strengths, and are used to treat eczema, psoriasis, lichen planus and other skin conditions, to reduce inflammation. They're also useful for skin irritation due to insect bites. They don't cure the problem but they do relieve itching, redness, inflammation and soreness. Short courses of mild steroid creams are very safe and can be bought from your pharmacist. Stronger steroids can cause thinning of the skin, so use them according to your doctor's instructions.

There's no question that high-dose steroids (usually prolonged courses of steroid tablets) can have side effects. That's why your doctor will monitor you carefully, both to check for side effects and to make sure you're taking the lowest dose to control your symptoms. Side effects include weight gain, increased appetite, high blood pressure, developing type 2 diabetes (or higher blood sugar if you already have it), acne, cataracts, glaucoma, inflammation of the stomach and stomach ulcers.

If you're on high-dose steroids, your doctor should give you tablets (usually'proton pump inhibitors') to protect your stomach. They can also increase your risk of osteoporosis (thinning of the bones), so you'll probably be prescribed a weekly tablet to protect them. Working with your doctor and attend regular check-ups (including blood pressure and blood sugar) will help you keep safe and get the benefit you need.

If you take steroid tablets for over 10 days, never stop them suddenly - your doctor will advise how to tail them off. It's also advisable to get a 'medic alert' bracelet just in case you're taken ill, so medical staff will know you're on steroid tablets.

With thanks to 'My Weekly' magazine where this article was originally published.

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. Patient Platform Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.