am i alone on this combination

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i have been taking mirtz 30mg and quetizapine 15mg for about 4 weeks now ,  have suffered depprsn and severe anxiety for 20 years this combination just knocks me out at night ,and i feel worse now than i did when i started taking these meds , shaking emotional so withdrawn , no life so unhappy , does anybody else feel like this,  

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  • Posted

    Hi Terry, I take both of those and also 300mg of venłafaxine.

    Both Mirt and Quetiapine have a sedative action, and the lower the dose, the more sedative they are.  15mg of Quetiapine is very low.

    You may need an additional AD which is more activating, and which you take in the morning.  Are you seeing a psychiatrist?

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    • Posted

      not seeing a psychiatrist at the moment , going to see my gp next week and they are going to refer me to one . i was on venlafaxine 100mg for about 8 years ,and the gp took me of it in a week , horrible coming of it , the venalaxife i believe had stop working for me , anxiety went through the roof , just feel at the moment the mirtz and qutpn are controlling me to many side affects when they should be making me feel better  
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    • Posted

      Psychistrist referral is good.  Is there a reason why your doctor didn't want to increase the dose of the venlafaxine rather than take you off it?  I'm not surprised your withdrawal was horrible, a week is a very short time to be taken off a drug you've been on for 10 years.

      I believe Mirtazapine helps my anxiety and sleep but didn't do anything for the depression which is why I was put on the Venlafaxine also. 

      I I hope you start to feel better soon and hope it goes well at the doctors

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    • Posted

      doctor did increase venlafaxine but it made me worse , mirtazapine really knocking me out at night , struggle to wake up in morning ,as well as quitepine makes me drowsy ,hopefully in time it will ease , got to give it time to work , thanks for your reply , how long have you been on this combination
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    • Posted

      I've been on Mirtazapine for 4 months, Venłafaxine 2 months and Quetiapine  for a month.  They say that the drowsiness wears off, I did feel a little drowsy when I first started but not anymore.

      As you suffered for such a long time, I think it's critical that you see a psychiatrist asap. 

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    • Posted

      do you think that this combination is working for you , i hope it is , i know different meds  work for different people , so i hope i can find a combination that works for me , having been on the one med venlaxafine for so long i know it might take a while to get one out of my system and to get another one in , have noticed a drop in anxiety but deppression still bad especially in the morning
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    • Posted

      Hi Terry, I can relate to the morning depression, I'm much worse in the mornings but improve as the day goes on.  My psychiatrist has ramped up the venłafaxine quite quickly.  I have good, bad and ok days.  I've suffered for 8 months so need to be patient and not expect miracles.  

      I can't imagine what it must have been like for you to live with this for 20 years.  Have you found any peace during this time?  Have you seen a psychiatrist?  

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    • Posted

      i have had some realy good spells over the years , months with no symptons at all , then out of the blue  it comes back , and every time it seems to be harder and longer to get over it , not seen psychiatist yet but hopefully soon
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  • Posted

    Hi Terry I've been on Mirtzapine now for nearly 6 months and I don't feel any better than when I started with them . I'm on 45mg once a day I feel just like I don't want to be here anymore , the doc says I'm grieving cause I've lost my mum my dad and my nephew in the last four years but I'm not so sure anymore . I hate feeling like this and having to justify to my husband why I feel like this all the time why can't I just be happy like other people some people say when people end their life that it's a waste but the way I feel now I can understand why they do it 

    very depressed and anxious to say the least 

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    • Posted

      Hi Nicola, I'm so sorry that you're feelng as you do, I know exactly how that feels and it's terrible.  

      6 months on mirtazapine is long enough to know if it's going to work or not.  I think you need to go back to the doctors.  Have you had bereavement counselling? Gen x

       

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    • Posted

      Hi Gen I go to counselling every week at the moment as its changes from day to day I seem to have like three days that are good and then I'm constantly sad and my heart is breaking I have to go back to the docs in a weeks time so I'm going to ask her again I may even ask to see a specialist I just can't seem to move forward with my life xxx
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    • Posted

      Hi Nicola, having good days is a good sign.  I know how awful it is for these to be followed by bad ones, but that is quite normal.  When you have your bad days are you able to do anything?  Do you find you have a complete lack of interest in doing things and get no joy out of anything? Gen xxx
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    • Posted

      hi nicola i know what you are feeling , i feel the same i just dont want to be here anymore , nothing i do seems to have any enoyment in it , just wake every day hopeing tomorrow will be better , i hate the way i feel , i smile just to make other people feel better but inside i am so sad , just want to feel normal even for a day , i will carry on with the meds , but if i dont see any inprovement in the next couple of weeks i will get my gp to change me to something else ,  i hope you find some help with your gp , but if this med coctail is not working for you  , get it changed , 
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  • Posted

    Hi Terry I've just spoke to my sister in law who is a psychiatric nurse and she thinks I need to see a psychiatrist as my father was a manic depressive and was on lithium for years so maybe I'm following him or maybe I need help with the grief as it has taken over my life and I just keep waiting for the next bad thing to happen so I'm going to see the doctor this week and demand to be referred to see a psychiatrist I will let you know how I get on but I'm not taking no for an answer this time I refuse to live like this anymore I don't care what it takes I'm prepared to do it to get the life I deserve and long for before its to late xxx
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    • Posted

      i think we are very much a like nicola , i lost a very good friend 20 years ago who commited suicide and i spent many years not allowing myself to enjoy life , i allowed the grief to be apart of my life every day re liveing every thought and emotion untill it seemed as if it was normal , it made me very emotional about death , worrying about those i cared for what if they died , even think of my own life and how the grief would affect those that i love , i hope you get you better and get the help you deserve , people say having a life is better than having no life at all , these people have never suffered with deppression , i am sure there is a way out of this dispair and i will find it , take care x
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