Anyone experience decreased effectiveness with longterm zoloft use?

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I have been taking zoloft for over a decade and am questioning whether it's still effective. Anyone out there having issues?

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    I have been taking Lithium for at least 30 years and Sodium Vaporate for the last 10 years. I can't feel any actual benifits from these drugs. But the main benefit must be that I am still alive.

    My identical twin commited suicide at 24 and my younger sister hung herself off the back of a door about 5 years ago.

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