Anyone get muscle tensing/dystonia like symptoms from coming off mirtaz?

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I been on very low dose (3.75mg) PRN, 2-3 times a week for the past 3 years. Well a month ago my muscles in my forearms and calves would start tensing up at rest. Killing my sleep in the process. I thought it might be some interdose withdrawal to mirtaz so I have been tapering off it, but not much tapering to do when I already took it so little/infrequently. 

Beginning to suspect a worse neuro disease, but was wondering if anyone else had similar type of withdrawal effects? 

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4 Replies

  • Posted

    Hi Joe

    Mirtazapine is not a PRN (take as needed) medication.  Taking it 2 or 3 times a week in of itself would cause many problems. It’s an every day AD. 

    Whatever provider told you to take mirtazapine as needed instead of daily was very very wrong. 

    The muscle issues you are experiencing are 100% mirtazapine w/d. 

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