Atrophic Vaginitis
Posted , 7 users are following.
Hi Everybody I have just come across this site and have found it very intresting. I have suffered for year's (I am now 56) with what I can only discribe as thrush and cystitic symptoms with out the discharge. I have had many swabs and water samples tests over the year's which normally come back normal, I was on HRT for over 5yrs after a total hysterectomy and stopped them about 4yrs ago. The symptoms just seem to flare up and I end up suffering with anx/dep which I am sure is brought on by my symptoms but then exculates. I am at present using Vagifem pesserys twice a week but still getting symptoms. I am going to try a canaston pessery tonight as I am getting desparate. I was at hospital last week for a follow up check after proplapse and vault lift operation and I mention my problem there but all they said was they couldn't see anything. Has anyone else experienced anx/dep with this condition. Sorry for going on but I feel like I'm going mad, and that no one believes me they put it down to anx/dep which I know dose make symptoms seem worse. :cry:
1 like, 21 replies
deb27931 Leah
Posted
It works in this situation by blocking receptors called cholinergic or muscarinic receptors that are found on the surface of muscle cells in the wall of the bladder. This prevents a chemical called acetylcholine from acting on these receptors. Acetylcholine acting on these receptors normally causes the muscle in the bladder wall to contract, and the bladder to empty. By reducing this, amitriptyline helps the muscle in the bladder wall to relax. This reduces unstable, involuntary contractions of the bladder, and thereby increases the capacity of the bladder to hold urine. This in turn reduces the need to pass urine. When used for this purpose, amitriptyline should generally only be used for a maximum of three months.