coming off Mirt

Posted , 5 users are following.


Got my self off mirt for a week now, was on 15mg for 4 months, tapered down over about 3 weeks, and felt ok, and better on 7.5 and even half that.

Was really taking it as much to help with sleep ( have always woken up many many times a night for past 30 years, but has got much worse last year or so) as depression, and it did help with my sleep but left me with little motivation to do anything, but now I am having really bad trouble with my sleep, and am tempted to go back to a low dose of mirtazapine to help with this, unless anybody has any good suggestions if alternatives.

As I say always had trouble with sleep for years and have never slept through the night as daft as it sounds, so can't put it just down to coming off mirt, as always had the problem. Depression isn't too bad at all really, but I am now getting depressed and anxious bout not sleeping.....

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7 Replies

  • Posted

    Hi there, what you say reflects what mirt does to me. I have been on it for a long time: it is a powerful sedative there is no mistaking that but like you, it really does rob me of motivation and after a while didn't help with the sleep issues. Again, like you, I have struggled with my sleep for years (15 approx), every night broken and disturbed sleep. I was always against sleeping tablets but my psychatrist prescribed a few different ones over the years and I now take Zolpidem (Stillnocht) with very few after effects. This particular tablet does help me unlike a lot of the others previously prescribed for me...the worst was Zopiclone. I don't get a perfect night's sleep, but like you I know how bad it can be when the pattern is heavily disrupted. I don't know if this helps you at all - perhaps talk to your GP. Best Wishes.  
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  • Posted

    Hi thanks it does help.

    I found that on a very low dose like 7.5 or even 3.5 my motivation was better, than on the 15 and sleep was still not to bad on such a low dose, which is making me think about going back on it.

    Not expecting a miracle cure, but if I don't sleep, then I am not in a good place, so guess fir me the sleep is a big issue with the mirt

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  • Posted

    Hi, I started on mirt to help me sleep as well as for the helped with the sleep for a few nights but then found that some days I could be wide awake until three or four in the morning I would then sleep until ten but would wake up tired....Am retired but still felt mirt made me feel worse hence my reason for wanting to come off it completely...Am looking at natural remedies and yes I have been on zoplicone too but didn't really think it helped may be yes talk to your gp and of course best wishes
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  • Posted


    This is a reply to everyone really...

    Did any of you notice a reduced appetite or even some weight loss on reducing your Mirt?

    I have been on and off lots of meds over the years... The most successful sleep aid I have had is Quetiapine.

    I am on 600mg at the moment but have been as high as 900mg, but I think this high amount is as I am using them to control Bi Polar and stop me going "high" psychiatrist had told me in the past that Q can be used in doses of around 50mg for Insomnia....

    I have met people in the ward base environment that have been on this dosage...

    Good Luck x

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    • Posted

      Thank you for your reply...

      I've just started on week 2 of a 4 week withdrawal plan... Nothing negative to report so far... ( hope I'm not speaking to soon)

      No weight loss as of present...

      Is the weight loss going to be significant? As I've got 4 stone to go....


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