Feel more depressed than ever!

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I wonder if anyone can help me.   I have reduced mirtazapine from 45mg to 22.5mg slowly, cutting the tablet into quarters every 3 weeks.  I have expereinced cold and hot sweats along with complete exhaustion.   But the one debiliating symptom is the deep depression, its seems to have come back with such force.  I cant stop cying, I have feelings of not wanting to be here anymore, anxious, scared of everything, completely irrational to name a few.   This feels worse than when i first started on them to help me with the exact same problems.  Has anyone else experienced these symptoms and if so do they eventually go or am I bound to these horrible tablets forever.  I feel like I am going out of my mind as I was starting to feel so much better hence the need to come off of the tablets.  I can cope with any physical side affects but the mental one is unbearable?  I really hope someonone can give me hope please? 

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4 Replies

  • Posted

    Hi W,

    Sorry to read of your suffering.  The very fact that the symptoms of depression have come back whilst withdrawing from Mirt' just proves it is the actual withdrawal and not any old symptoms; a lot of people can get caught up in this thinking they need to return to the full dose.

    Mirt' is a tricky AD to get off as the sympoms of a WD done too quickly brings on these, and other symptoms which can 'seem' unbearable.  You don't say how quickly you have been withdrawing, but there is a rule of no one than 10% every 3-4 weeks, or even 5% every 2 weeks (which is the wd plan I am following right now).  So I think your symptoms do sound like the wd is way too fast, the crying, depression or feeling low, anxiety and especially the fatigue, all wd symptoms.

    Can you just give a little detail of how you have been withdrawing, a little time line  including how long you have been on Mirt? ... 

    In the meantime, just carry on taking your med before bedtime, don't do another drop yet, these symptoms won't last forever, we just have to take it slower and all will be well again.

    Wishing yo well, glad to be able to chat, hiope it helps a little.  x

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    • Posted

      Hi C

      Thank you so much for replying to my message.  I was originally on 45mg and now on 22.5g.  I have been cutting my tablets into halves and changing every 3 weeks.   Therefore my next dose will go down to 15mg for 3 weeks.   I know I am probably going down too quickly but I have put on a stone and that is making me so unhappy, I cant fit into any of my clothes anymore. so not only do I not feel like myself anymore I dont look like me either!!  Do you think this is why I have been feeling so depressed ? 

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  • Posted

    Hi want

    yes definitely I have felt like this. I reduced my mirt and four days later I thought death would be kinder! My mind was in a high state of stress, I cried buckets and even tried to call a crisis line for the first time in my life! (I got an automated message saying busy call back later!) That automated message seems funny now but it wasn't at the time. I had to go back to my original dose, after a couple of days I felt better. I think you are experiencing an extreme reaction of a chemical imbalance and your brain is trying very hard to regulate itself with less mirt .

    you may need to up it just a little and taper even more slowly. I know you want to come off the mirt, it's achievable but maybe at a slower pace.

    wishing you better

    god bless ♥

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    • Posted

      Hi Lorraine,

      Its not funny at all but how irronic is that the crisis line was on a message service!! I too have felt very suicidal and contacted The Samaratins and was told that if I wanted to take my life that was my choice but maybe I should have a think about it first, I was absolutely shocked, what help was that!!! Thankfully I stopped feeling that way and have only just started feeling a bit like that again after the withdrawal of these horrible tablets.  Sorry you have experienced the same as me but at least I know Im not going mad,  I really wish there was an easier way.   Good luck with yours too x

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