Feeling awful

Posted , 5 users are following.

Hi there,

I'm still having some issues with Mirtazapine, I started on 15mg about 3 weeks ago. Two weeks in to taking 15mg I started to become more depressed and anxious, with an increase in nausea. So my GP upped my dosage to 30mg.

Another week passed, and the 30mg made me feel worse, I started to obsess over things, I kept panicking and feeling sick. I had become more depressed and anxious.

I went to my Doctor on Thursday, who said that I was increased to 30mg too quickly. And I was likely having a bad reaction. He reduced my dose back to 15mg, and gave me domperidone for the nausea.

While I feel slightly better, I still keep having obsessive thoughts and panicky moments. The Domperidone doesn't seem to do much for my nausea either. And I keep getting strange symptoms:

Hot/burning sensation on my face

Small moments of shaking


States of panic and worry

Low mood

Moments of increased emotions (usually teary)


moments of appetite/ then no appetite at all

I keep telling myself that they are most likely side effects and they will go away. I've just never had this sort of problem with Mirtazapine before. I took it for about over a year back in 2016, but it failed on me back in November. Since December I've been trying a few other antidepressants that didn't work well for me. So I went back onto Mirtazapine.

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4 Replies

  • Posted

    Hi, I completely understand what you are saying that sounds like what happened to me, I never want to take it again!

    Hope you get sorted soon

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  • Posted

    Hi robert.

    I have just had my dose upped to 30mg as 15 was not helping. My mood and depression have fallen and i feel like i have the flu with a tight chest and shaking hands.

    I am a recovering alcoholic and it is very similar to the effect of having no drink. 

    Sometimes i get so low i have suicidal thoughts or thoughts of going back on the drink as when i was a drunk life passed by and suicidal thoughts were not there unless things got real bad. But taking mirtazapine is supposed to help nd i cant really see how it  works but my doctor says it will get better and settle down.

    Well now i have 28 tabs at 15mg and 28 at 30mg with a huge urge just to take the lot and hope its enough to end this nightmare for good.

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  • Posted

    I have experienced some of the symptoms you described, nausea, anxiety/panic, which will come from nowhere, I have decided to kick this drug into touch, it appears we have to suffer this to get to the other side. Stay strong and take heart that many of us are experiencing very similar feelings to you.  You are not alone, whoops there goes the buzzing in my face and head again.  Happy Days 
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    • Posted

      Hey Anghared,

      I'm trying to keep it together as best as I can, I visited my doctor yesterday and she said the symptoms I had were likely to be due to my anxiety issues. She's given me metoclopramide tablets to help with the nausea. They do help with eating, but I just hope that the other symptoms dissipate soon.

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