From Citalopram to Fluoxetine - anyone experienced it?

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Hi! I have been on citalopram 20mg for about 18 months. It was working well, but in the last 2-3 months my mood has deteriorated. The only side effect experienced on citalopram was lack of sexual drive. Today I spoke to my GP and she advised to change my medication. She prescribed me Fluoxetine 20mg hoping it will resolve the side effect and improve my mood. Has anyone experienced this change in drugs? Was it good or bad?

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  • Posted

    Without intruding can you explain the deteriorated mood a little more. IE is there any thing else that could have made this happen, is it mood or thoughts as well.

    did you feel stable on citalopram and cope well. alot of people may disagree with me but if it has worked well for over a year i would not be happy rocking the boat with a change of medication, people can play with your life but they dont have to live in your body so its easy to just experiment on others, ive seen it and hate it.

    Im a carer for someone who has been on these for over a decade, nhs would like to play guinee pig them and have tried a few times but i stop them before they start. The person i care for is stable and doing very well so why should they mess with her.

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    • Posted

      Well, my mood went downhill and I started having negative thoughts again. I had causes of stress at work, I feel at a standstill in my career and in my relationship. My self esteem has been very low. I have just turned 30 and I feel I haven't achieved anything in my life - which is not true if you look at it objectively, but my mind is playing tricks on me. In a couple of occasion I felt it really didn't matter if I lived or died. I had suicidal thoughts out of desperation in the past, before being on medication, but now I feel I could really do it, and with a clear mind. I had councilling last summer and it really helped, but lately I have not been able to apply the exercises I've learnt. I think my GP changed the medication to see if I can rid of the side of the citalopram and get back to my usual sexual life. My boyfriend has been very supportive throughout my treatment, we had a good all around relationship, but after a year and a half of hardly any intercourse and lack of libido I feel pretty down.
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  • Posted

    I switched from citalopram to fluoxetine as citalopram caused me sexual problems. Ages to reach orgasm and some times ED.


    Ok when making the switch there is one very important point to remember. Citalopram is out of your system in about 3 days BUT fluoxetine will take about 4 weeks to reach the steady state level in your blood. So this means if you stop citalopram dead and go straight to fluoxetine after a day or 2 you will have a withdrawel symptons for around 2 weeks while the fluoxetines builds up in your blood. If I done the switch again with the knowledge I have now I would 'cross taper'. So I would switch to a half dose of citalopram for the first week while taking fluoxetine and then stop the citalopram after one week IF I had no withdrawel symptons. Otherwise I'd wait a few more days before stopping citalopram.

    FYI all ssri's are well known to cause sexual side affects. In fact most antidepressants do with the exception of a few. BUT citalopram for me was the worst in that department.

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