Has anyone else felt total exhaustion on Mirtazapine?

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Having been on Citalopram for ages - lots of horrible stuff happened and I aske dmy Dr if changing Antid would help. He suggested Mirtazapine. So 3 weeks later Im on the double dose and I can't cope with my anger but most of all the exhaustion - if its not these pills then I must be dying because how I feel is not normal in ANY way. I have cried for about 4hrs tonight - no idea how I am making it to work but I can bearly climb 3 stairs.

Seeing my very young and green Dr in 2 weeks but I can't wait to get off these they are AWFUL. I have never felt so terrible. Does anyone out there feel the same?

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6 Replies

  • Posted

    AllyF, I'm very sorry you feel so terrible. Have you expressed your feelings to your doctor? You must get

    help soon.I had mild depression and my MD prescribed the lowest dose of mirtazapine 15 mg.

    In the beginning it did nothing to reduce my depression and made me very tired. I did not want to get out of bed in the morning.

    I stopped taking it and then did not sleep well.

    I thought to myself - well sleepiness is better than insomnia so I resumed taking it but a lower potency. The doctor told me to cut the 15 mg. table in half which I take at bedtime. It's the

    the only antidepressant I have ever used. Not immediately but it slowly alleviated my sadness and while

    I still feel like taking a nap in the afternoon I can pretty much function without one.. I have a friend who

    had very severe depression .She was taking many prescribed medications but was close to death -

    she wasn't eating and was down to 70 pounds.

    Her doctor switched her to mirtazapine. She has been on it now for a few years.

    She said it saved her life. I think that one sometimes has to find the right dosage and gradually the side effects are diminished. They may never totally disappear but enough so that one can lead a normal

    life. I hope that you find some relief soon. I can't even imagine what you are going through. Good luck

    in your search for the right medication to bring you back to a feeling of wellbeing.

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  • Posted


    The initial side effects can be terrible for most of these anti-depressants, and you are obviously suffering something really horrible.

    Perhaps see your GP a.s.a.p expressing your concern to the surgery receptionist and insist (politely) on an immediate appointment - no matter which GP you see. Ask for reassurance about how you are feeling and the side effects, it may well be that the side effects settle down, but your GP needs to know in case they don't suit you.

    I have quite recently been prescribed Mirtazipine but I was taken off and onto another anti-depressant, because although I felt good mentally, I had some not nice physical side effects which disappeared when stopping Mirtazipine.

    We are all different and it seems that these ant-depressants affect us all differently, which you may know already.

    It has to be your choice what you do, this is just an opinion.

    I do wish you well

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  • Posted

    Good advice, David. I hope AllyF gets professional help soon.
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  • Posted


    Thanks for responses. Have spoken to my Dr who has advised stopping immediately. He is seeing me tomorrow to see if I feel any better, Very scary but altho still very dizzy and tired - feel a little better.



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  • Posted

    AllyF - So glad you have contacted your MD and are stopping mirtazapine. Good luck with a total and rapid recovery from the bad side effects.

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  • Posted

    I'd like to say the same as AllyF - and best wishes.
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