I have suffered with IBS for nearly 10 years. It is usually in the form of constipation and horrendous bloating, however occasionally I get agonising cramps to the point of almost passing out. I do have a high stress job which i know doesn't help, but I'm not going to give that up, so I had to look for other options. Over the years my GP has referred me for colonoscopies and biopsies of the bowel. I have tried mebeverin, buscopan, peppermint oil tablets, all sorts. None of it made a difference, until I found INTESTAID IB about a year ago. I buy it from Boots where it is often on their 3 for 2 offer, because it isn't cheap. It costs about £25 for a month's supply, but it is totally worth it. I'm sorry if this sounds like an advert - I promise it isn't. Initially you have to take it twice a day for the first month. I don't know how it works, but this seems to settle down the intestines/bowel. After the first month, my symptoms had almost disappeared and then I could reduce it to one tablet a day. I'm not going to say that I never have any problems at all, but I would say that my symptoms have reduced by about 90%. All I would say is try it for a few months. Quite honestly, I was at the stage where I would have tried anything, because I felt so ill for much of the time.