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Has anyone found a good replacement for omeprazole ?

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  • Posted

    I Did not find omeprazole to work for me, I gave it about a month with little to no improvement.  My doctor then suggessted prevacid (which is also the medication that worked for my mom)  I was on it 2 weeks and felt significant improvement in my throat.  I had barely any voice left and a very scratchy throat.  I am now on week 4 and doing much better.  I did give up coffee/soda and spicy foods etc for a solid 3-4 weeks when things were really bad, but I have no been able to gradually bring those things back.  If you haven't tried Prevacid yet (I get the name brand right at the drug store) i highly suggesst giving it a try.  

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  • Posted


    Check whether you need a PPI (eg omeprazole). If you only occasionally get excess acid, you can manage it with ordiary antacids (eg Tums, Rennie) or with an alginate like Gaviscon which has the added benefit of providing a temporary extra lining to th eoesophagus and, floating like a raft on stomach contents, helps reduce reflux.

    However, if you have acid refluxing regulalrly you should discuss it with your doctor. You may need an acid suppressant (ie an H2 blocker like ranitidine or a PPI like omeprazole. )

    If you need a PPI, you should take the minimum effective dose for the shortest necessary time and under the monitoring of a doctor. It is best to take it half an hour befor breakfast.

    Some people are worried about the reports popularised by te alarmist press that PPIs may be linked to other conditions. These scare stories are mainly due to the fact that popular media don't seem to know th edifference between correlation and causation. (If you vsit the www BarrettsWessex org uk website, you'll find a good page on this subject "PPI dangers" under the TREATMENTS / Tabs headings. )

    If you think you are getting side effects specifically from the omeprazole, ask to try a different PPI instead.

    Some people need to take PPIs for life. They are literally saving lives with a meta analysis of all the relevant research recently concluding there's a 71% reduction in risk of acid reflux leading to cancer.

    If your problems are mainly reflux rather than acid, you'll need to follow the lifestyle modification advice or have reflux reduction surgery (eg fundolication) .

    For more information see the free book / website: www DownWithAcid org uk

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  • Posted

    i was on nexium for a number of years which gave relief from indigestion but caused lots of other problems so i weaned myself and now eat an apple after a heavy meal works for me.
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  • Posted

    Hi Sue,

    I found nexium a better replacement for omeprazole.

    Took it for a year then had fundiplication op to fix reflux and hiatus hernia.

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