Just increased my dose of mirtazapine to 45mg 9th day awful anxiety and agitation

Posted , 5 users are following.

I have been on mirtazapine for around 4 Months 7.5 15 30 Now 45mg for over a week and my anxiety is worse than ever will this settle down?

0 likes, 5 replies

Report / Delete

5 Replies

  • Posted

    has it worked at all ?

    Report / Delete Reply
  • Posted

    hello, increases in anti deps tend to initially increase anxiety for 2 to 3 weeks, before it settles down. happened every time with my increases. sometimes though, it doesnt settle down, and can get worse, and stay like it. an increase of 15mg of mirt is quite high compared to other anti deps. its 33% of the maximum dose, whereas most other anti deps you increase by 25%. you could drop to 37.5mg instead, which will give you an increase, just not as much, but getting used to 37.5mg should be easier than 45mg. if the anxiety gets worse, then drop to 37.5mg. if its bad, but not worsening, try to stick with 45mg.

    Report / Delete Reply
    • Posted

      Nigel is spot on. That is my experience as well with Mirtazapine. It's strange that Mirtazapine only comes in 3 doses as the responses to 15, 30 and 45 can be very varied. A pill cutter is a must when negotiating changes with Mirtazapine in my experience.

      Report / Delete Reply
  • Posted

    If you bin on it for 4 months reduce slowly then stop taking it and bye a antihistamine called sominex/phenergan it will stop all withdrawal from mirtazapine and it will stop anxiety sominex /phenergan is not addictive the owill only get withdrawals from if you take it for years Remember this the human body connot build a tolerence up to antihistamines its impossible so your 1000000% safe on phenergan Mirtazipine is the worst drug withdrawal out there get of it before you build a tolerence up for mirtazipine its a long dirty withdrawal remember doctors are full off s**t

    Report / Delete Reply

Join this discussion or start a new one?

New discussion Reply

Report or request deletion

Thanks for your help!

We want the forums to be a useful resource for our users but it is important to remember that the forums are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the forums is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.

newnav-down newnav-up