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Mirtazapine Constipation & Groggy

Posted , 3 users are following.

dani04856
dani04856

Hello ,

I started Mirtazapine around 4 weeks ago. I am taking 7.5 mg....I have terrible constipation and grogginess. I am wondering the grogginess goes away? I like to go to the gym in the morning but having a hard time doing so. On a positive note, I was able to get off Lorazepam which I used for sleep for close to 6 years.

I have gaine around 5 pounds, however I was binge eating prior to this drug so I am not going to attribute it totally to Mirtazapine.

If the grogginess continues I might have to get off this drug.

0 likes, 2 replies

2 Replies

  • SerotoninSurfer
    SerotoninSurfer dani04856

    Posted

    Hi Dani, i've been on Mirtazipine for around 6 months now. The grogginess does go but Mirtazipine is more sedating the lower the dose you are on.

    As a general rule of thumb the doseages have the following impact but everyone metabolises these drugs differently so this is a very generalised view after my own experiences and others i have engaged on this forum.

    7.5 - 15mg - very sedating due to antihistamine receptor antagonist (treats insomnia)

    15mg - 30mg seretonin and antidepressant properties kick in (treats anxiety and depression)

    30 - 45mg - activating and robust for countering severe depression (severe depression)

    I take 30m Mirtazipine in the evening and 50mg Setraline in the morning and starting to feel almost back to normal after a horrendous rollercoaster of trial and error with medication

  • dani04856
    dani04856

    Posted

    Thank your for your response, what week did the grogginess go away for you? Also, were you affected by either constipation on weight gain?

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