Mirtazapine worsened depression

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I have been back on Mirtazapine for 2 weeks now (45mg) and although I feel brighter today, I think it has definitely worsened my depression. I know I have to give it time to work but has anyone experienced worse depression in the beginning of treatment? 

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  • Posted

    Where u on another medication before going back on Mirt if so it could be the switch between the two that is causing it I been on Mirt for anxiety / depression  and I started off at 15 mg.. 45 mg of Mirt is a high dose to start off on 
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    • Posted

      I was on Mirt for 6 weeks (2 of those were on 45). I started feeling a bit odd/emotionally numb/like a zombie kind of feeling and my doc told me to stop but I could handle it and after 5 days went back on it but I think Mirt was more or less out of my system so when I resumed, I felt like depression got worse... two weeks back on it and I am just starting to feel a bit better. 
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  • Posted

    Hi Ala when I first started mirtazapine they made my depression and anxiety worse fast forward 8 month and now my depression is alot better, I still get the odd bad day, they don't seem to do much for my Anxiety though. Hope this helps.

    Leanne

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    • Posted

      Thanks for responding it helps to know that it is not helping for anxiety I find it is not helping my anxiety at all and seem to be making me have more anxiety then normal 
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    • Posted

      Leanne, it’s so frustrating when we have to wait so long for the meds to work.... it’s lile eternity when you are feeling depressed... what dose you are on?
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  • Posted

    I'm on 45mg. It is hard having to wait so long but hang on in their. Definetly doesn't help my anxiety at all kat it's a daily struggle with my Anxiety... I'm trying exposure therapy now which is putting myself in difficult situations and try to get through them.

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  • Posted

    Hi there. I just wanted to say that I felt suicidal for the first two weeks of my meds. 

    It really enhances all the bad stuff. 

    I hope that reassurance helps. 

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