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I started to feel a little brighter about 3 weeks after starting Mitrazapine (15mg) having completely weaned off Sertraline. At about week 5 I started Ropinirole 0.25 mg and now 0.5 mg for my restless legs and muscle tightness. Just after week 6 on Mertrazapine I started feeling very low again and this has continued for 5 days. Could this be the conbination of drugs or could it be that I need to increase my dose of Mertrazapine? I was so hoping I could keep on the lower dose but Zi can't be like this leading up to Christmas. Please has anyone else been on this combination of medication?
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