Propanolol plus Mirtazapine and Citalopram

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Hi, I've been prescribed Propanolol for anxiety, 10mgs twice a day. I have been on this for just over a week now. Since the 7th day of taking, I felt exhausted to the point where it was an effort to walk and I had to go to bed. My psychiatrist has suggested cutting the dose in half and I am taking 5mgs twice a day, using a tablet cutter to cut the tablets. Has anyone else had these symptoms of complete exhaustion on Propanolol? I am in complete despair. Additionally, am taking Mirtazapine 11.25mgs (cutting down from 15mgs) and Citalopram 40mgs.

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  • Posted

    Hi Vikki , i tend to agree with Sarah that it might be the reduction in the Mirtazapine that's causing your Fatigue. Take care an best wishes Lloyd from Oz

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  • Posted

    Thanks, Sarah and Lloyd. That's a good point. Although I used Propanolol once before when I had anxiety and it caused tiredness and I wasn't taking any other drugs at the time. Probably a combination of the two - cutting the Mirtazapine and introduction of Propanolol - that's caused the extreme fatigue. My Psychiatrist couldn't understand why I was so tired with taking the Propanolol so that could explain things.

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    • Posted

      Hi Vikki , good luck with your medications and hope things settle down for you very soon. Take care Lloyd from Oz
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  • Posted

    I was put on propanalol by gp, taken off by hospital. It's a beta blocker, given to people with heart trouble, it slows the heart rate & slows you down too, I was exhausted on it. That will be one reason for your tiredness.

    The other reason will be your reduction in Mirtazipine, the less you take of mirt, the more sedative it is.

    I'm just on Mirtazipine 15mgs now & apart from weight gain & tiredness, it does the trick.

    Ask your gp to come off propanalol? 👍

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    • Posted

      Thanks, Brenda. The Propanolol was given to me for palpitations which I get as a result of my anxiety and has really helped with these symptoms which I find frightening and are feeding my anxiety. So I have slightly reduced the dose of Propanolol and am hoping I'll get used to taking it. It would be a shame to completely stop it especially if the lower dose works initially, then can be increased once I get used to it, hopefully!

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