What causes a keloid scar to form?
Science hasn't yet managed to explain why some people go on to develop keloid scars after their skin is damaged, and others don't. But we have a pretty good idea of how it happens.
Keloid scars form because the normal process of scarring, that we all have, goes into overdrive:
- Normally when the skin is damaged, fresh skin is laid down to heal the damage but then the damaged area you see gradually fades away (the medical term for this process is 'involution').
- In a keloid scar too much collagen is laid down in the skin after the damage has happened. It heals 'too much'.
- Then, instead of simply fading away, the scar tissue just stays where it is.
- The people who get keloid scars are usually those who have black skin and who originate from Africa or the Caribbean.
- No one quite knows why this happens. It seems to be unique to humans: other animals do not get keloid scars.
How does a doctor diagnose a keloid scar?
- There is no particular test for a keloid scar. It is diagnosed from the clinical story (a slow-growing overgrowth of a scar, usually in a dark-skinned person), with the scar growing beyond the location of the original skin damage.
- Occasionally a keloid scar can mimic other skin tumours.
- Very rarely, a skin tumour like a dermatofibroma or a soft tissue sarcoma can be mistaken for a keloid scar, or vice versa.
- In that case, a biopsy will need to be taken by a specialist. A biopsy is a procedure where a sample of tissue is taken for further analysis.
- The biopsy will be looked at under a microscope and a specialist (histopathologist) will be able to see the typical microscopic features of a keloid scar: a swirling nodular pattern of collagen fibres.
- Note: a biopsy is hardly ever necessary because the history - ie the patient's story - and the appearance of the skin growth are very typical of a keloid scar.
What do keloid scars look like?
This image shows a keloid scar on a 4-year-old child's toes, that formed following surgery he had at the age of 2 years:
The image below shows a keloid scar on a woman's ear, after an ear piercing.
Images from Openi® (Open Access Biomedical Image Search Engine)
Further reading and references
Shamsi Meymandi S, Rezazadeh A, Ekhlasi A; Studying intense pulsed light method along with corticosteroid injection in treating keloid scars. Iran Red Crescent Med J. 2014 Feb16(2):e12464. doi: 10.5812/ircmj.12464. Epub 2014 Feb 5.
Gauglitz GG, Korting HC, Pavicic T, et al; Hypertrophic Scarring and Keloids: Pathomechanisms, Current and Emerging Treatment Strategies. Mol Med. 2010 Oct 5.
Davidson S, Aziz N, Rashid RM, et al; A primary care perspective on keloids. Medscape J Med. 200911(1):18. Epub 2009 Jan 20.
Viera MH, Amini S, Valins W, et al; Innovative therapies in the treatment of keloids and hypertrophic scars. J Clin Aesthet Dermatol. 2010 May3(5):20-6.
I had a small mole removed fom my chest, but the stitches split and have left me with a huge keloid scar. I'm so self-conscious of it as it right in the middle of my chest, so I can't wear any low...Guest
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