Steroid medicines (known as corticosteroids) are man-made versions of natural steroids. These are produced in the body by our adrenal glands. Steroid medicines come in various forms. Those taken by mouth are known as oral steroids and can help in many diseases.
What are oral steroids?
There are several different forms of steroid medicines. The form discussed in this leaflet is the tablet form, taken by mouth, called oral steroids. Other types of steroids include creams, inhalers, drops and sprays. These are discussed in the separate leaflets called Topical Steroids (excluding Inhaled Steroids), Topical Steroids for Eczema and Inhalers for Asthma.
What do they do?
As above, steroids both natural and medicinal versions, settle inflammation and dampen down the actions of the immune system. They also prevent cells in our body from multiplying, by shutting down production of DNA, the molecules which carry our genetic code within every cell. Other effects include a narrowing of blood vessels and influences on various hormones.
Are there different types?
Yes, broadly speaking there are two groups of oral steroids. The most commonly used group is glucocorticoids. This group includes steroids such as:
The other group is called mineralocorticoids. This is the type usually used for replacing steroids the body isn't producing itself, and the common one used is fludrocortisone.
They usually come as tablets, but some also come as dispersible tablets or solutions.
Where can I get them?
From a pharmacy, oral steroids are only available with a prescription from your doctor. This is because it is safest to take them under medical guidance.
Do they work?
Generally steroids are extremely effective, when prescribed appropriately.
Can I take steroids if I am pregnant or breast-feeding?
Your doctor will help you weigh up the pros and cons but, generally speaking, steroids can usually be used safely in pregnant or breast-feeding women. The lowest dose possible for the shortest possible amount of time would be used. It is thought that when used in early pregnancy, taking steroids may slightly increase the risk of your baby having a cleft lip and/or palate.
Further reading and references
British National Formulary; NICE Evidence Services (UK access only)
Corticosteroids - oral; NICE CKS, August 2015 (UK access only)
Gupta A, Gupta Y; Glucocorticoid-induced myopathy: Pathophysiology, diagnosis, and treatment. Indian J Endocrinol Metab. 2013 Sep17(5):913-6. doi: 10.4103/2230-8210.117215.
I was prescribed 40mg of prednisolone per day to treat me for Giant cell artritis (i'm in my mid 30's!) I took it immediately after food last night and went to bed a few hours later. I finally fell...victoria 26089
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