Professional Reference articles are written by UK doctors and are based on research evidence, UK and European Guidelines. They are designed for health professionals to use, so you may find the language more technical than the condition leaflets.
Synonyms: the ischaemic necroses
This group of conditions mainly affect children; and all involve a defect in ossification at either the bone epiphysis (growing plate), the joint surface itself, or at an apophysis (bony projection).
When articular surfaces become ischaemic, osteochondritis develops - this is associated with avascular necrosis and sclerosis.
The underlying defect in the different osteochondroses is usually not known but the mechanism often relates to trauma or stress on the area affected. Commonly there is breakdown of the area with poor mineralisation. Articular surfaces that develop osteochondritis may fragment (osteochondral fracture = osteochondritis dissecans), eg in the knee, elbow, ankle, etc.
The osteochondroses are often classified as follows (click on links for separate related articles):
- Articular osteochondroses:
- Non-articular osteochondroses:
- Epiphyseal osteochrondroses:
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Further reading & references
- Panner's Disease; Wheeless' Textbook of Orthopaedics
- Adolescent Blounts Disease, Wheeless' Textbook of Orthopaedics
- Bui-Mansfield LT; Osteochondritis Dissecans, eMedicine, Aug 2009.
- Pessler F, Sherry D; Osteochondroses,Merck Manual, 2008.
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