Diabetes research
Type 1 and type 2 diabetes, prediabetes and related metabolic research.
452 indexed studies · 208 currently recruiting
Top conditions in this hub
- Type 2 Diabetes71
- Diabetes Mellitus, Type 239
- Diabetes Mellitus35
- Diabetes31
- Obesity31
- Type 1 Diabetes26
- Type 2 Diabetes Mellitus25
- Diabetes Mellitus, Type 122
- Type 1 Diabetes Mellitus14
- Cardiovascular Diseases13
- Hypertension13
- PreDiabetes11
- Heart Failure10
- Diabetic Foot Ulcer10
- Insulin Resistance9
- Gestational Diabetes9
Recent studies
- Recruiting
Metabolic Phenotyping and Follow-Up of Patients With and Without Diabetes After New Onset of STEMI
This study looks at how heart attacks affect people with and without diabetes. We want to understand more about metabolism, how bodies use energy, and their link to heart health to help improve treatments for people who've had a heart attack.
Germany - Recruiting
The Force Frequency Relationship in Heart Failure and Diabetes Mellitus: a Metabolic Aetiology?
This study looks at how your heart's pumping power changes with heart rate, especially if you have heart failure and/or diabetes. We want to understand if problems with how your body uses energy (metabolism) are involved, hoping to find better treatments.
United Kingdom - Enrolling by invitationNA
Effects of Dried Whole Fruits on Metabolism in Diabetes
This study looks at whether eating dried Saskatoon berries can help people with prediabetes or new type 2 diabetes manage their blood sugar and gut health, compared to eating dried apple slices.
Canada - RecruitingNA
Time Restricted-EAting for Type 2 Diabetes and MEtabolic Health: the TEA TIME Trial
This study looks at how 'time-restricted eating' (eating only within certain hours) affects type 2 diabetes. Researchers want to see if it helps manage blood sugar and improves how the body uses insulin, especially for people recently diagnosed with type 2 diabetes.
Canada - RecruitingNA
Rebalancing the Fat Content of the Heart and Muscles
This study looks at a new diabetes medicine called Semaglutide, combined with diet or exercise. We want to see how it affects the amount of fat in the heart and leg muscles of people with type 2 diabetes. It's about finding better ways to manage diabetes beyond just blood sugar.
United Kingdom - Recruiting
Capillary OGTT Study
This study is looking for new, easier ways to test for diabetes (Type 1 and Type 2) in children and young people. Instead of tricky hospital blood tests, we want to see if finger-prick tests at home or skin sensors can give reliable results.
United Kingdom - RecruitingNA
Adipose Tissue Storage in the Rapid Remission of Hepatic and Cardiac Metabolic Dysfunction After Bariatric Surgery
This study looks at how weight loss surgery (bariatric surgery) helps improve type 2 diabetes by studying how the body's fat stores change. They want to see if these changes in fat are key to why diabetes gets better after surgery.
Canada - RecruitingNA
Role of High-Throughput Whole Genome Sequencing for the Diagnosis and Care of Atypical Diabetes
This study looks at how new DNA testing (whole genome sequencing) can help diagnose unusual types of diabetes. It compares this advanced test to current methods to see if it leads to better understanding and care for patients with difficult-to-diagnose diabetes.
France - Not yet recruitingNA
SENSILINS: Impact of Cephalic Phase Insulin Release Induced by an Environmental Food Odor Stimulus on Glucose Homeostasis According to Insulin Sensitivity Level
This study looks at whether smelling pleasant food before eating affects how your body handles sugar. It's for adults with or without obesity and insulin resistance, to see if smell can improve blood sugar control.
France - RecruitingNA
Exploratory Evaluation of the Effect of Cholestyramine on Serum Levels of POPs in Obese Female Patients
This study looks at whether a medicine called cholestyramine can help reduce levels of certain chemicals in obese women before weight-loss surgery. These chemicals, called POPs, can build up in fat and might be released after surgery, potentially causing health concerns for mothers and babies.
France - Recruiting
Balancing "bad" and "good" immune cells: testing a novel method for monitoring an immunosuppression strategy in people with Type 1 diabetes
This study is testing a new way to quickly check if treatments for Type 1 diabetes are working. It involves two medicines to help balance immune cells and aims to find better ways to stop the body from attacking insulin-producing cells.
United Kingdom · England · Wales - RecruitingNA
Laser Therapy for At-Home Treatment of Diabetic Foot Ulcers - Canada
This study looks at whether a special home-use laser device, called B-Cure Laser, can help diabetic foot ulcers heal faster. Participants will use the laser alongside their usual treatment to see if it makes a difference compared to standard care alone.
Canada - Active not recruitingNA
MyDiaMate For Remission Of Diabetes Distress In Type 1 Diabetes (MyREMEDY)
This study looks at whether a self-help app called MyDiaMate can improve the mental well-being of adults with Type 1 diabetes. Many people with Type 1 diabetes experience stress and worry, and this study compares using the app to regular care to see if it helps.
Germany · Netherlands · Spain - Completed
Smart technology for diabetic foot monitoring
This study looks at smart socks to help people with Type 2 diabetes. It aims to measure pressure on the feet during walking to prevent serious foot problems like ulcers. Researchers want to see if these socks can spot early signs of nerve damage in the feet. Join if you have Type 2 diabetes and can walk.
United Kingdom · England - RecruitingPHASE2
Study of WAL0921 in Patients With Glomerular Kidney Diseases
This study is testing a new medicine, WAL0921, for people with certain kidney conditions, like diabetic kidney disease or rare kidney problems. It aims to see if the medicine is safe and effective in helping your kidneys. Some people will get the medicine, and others a dummy treatment.
United States · Australia · India - RecruitingNA
Pilot Study Evaluating Safety of ExOlin® in Patients With Poorly Controlled Type 1 Diabetes
This study is testing a new treatment called ExOlin® for adults with type 1 diabetes whose blood sugar levels are hard to control, even with insulin pumps. It's looking to see if ExOlin® is safe and can help manage blood sugar better, especially for those who often have very low or very high sugar levels.
France - Not yet recruitingNA
A Multi-centre Trial to Assess the Efficacy and Safety of the Omnipod 5 System in People With Type 2 Diabetes Undergoing Haemodialysis
This study looks at a new automated insulin system, Omnipod 5, for people with type 2 diabetes and advanced kidney failure on dialysis. It aims to see if it improves blood sugar control and quality of life compared to usual care.
United Kingdom - RecruitingNA
Effect of Hyperglycaemia and Moxifloxacin on QTc Interval in T2DM
This study looks at how high blood sugar and the antibiotic moxifloxacin affect the heart's electrical rhythm in people with type 2 diabetes. Researchers want to see if moxifloxacin's effect on heart rhythm is worse when blood sugar is high or insulin is low, to improve patient safety.
United Kingdom - Active not recruitingPHASE4
A Study of Cardiovascular Events iN Diabetes Plus
This study is for people with type 2 diabetes who haven't had a heart attack or stroke. It checks if a tablet called semaglutide can safely lower risks of heart problems, strokes, and death from heart issues over about 5 years, all done from home.
United Kingdom - Not yet recruitingNA
Quantifying Artificial Pancreas-related Changes in Diabetic Neuropathy
This study looks at how new insulin delivery systems, like insulin pumps and 'artificial pancreases', might help people with type 1 diabetes who have nerve damage (neuropathy) by improving blood sugar control. It compares them to standard insulin injections.
United Kingdom - Recruiting
Who Will Benefit From Bariatric Surgery for Diabetes?
This study looks at why some people with type 2 diabetes benefit from weight-loss surgery (Roux-en-Y gastric bypass) more than others. Researchers want to understand if things like body fat, genes, and gut hormones play a role in putting type 2 diabetes into remission after surgery.
United Kingdom - Active not recruitingNA
ARIADNE: A Study of Weight Loss for Diabetes Treatment and Wellbeing
This study looks at how a special low-calorie diet affects people with type 2 diabetes and concerns about their eating habits. We want to see if this diet helps with diabetes without causing problems with their relationship with food. It will help us understand if this diet is safe for everyone.
United Kingdom - Active not recruitingPHASE3
Safety and Efficacy of AT-001 in Patients With Diabetic Cardiomyopathy
This study is testing a new drug, AT-001, for people with heart problems caused by diabetes, known as diabetic cardiomyopathy. Researchers want to see if AT-001 is safe and effective in preventing the condition from worsening into full-blown heart failure.
United States · Australia · Canada - Active not recruiting
Smart Watch Insights for Prevention of Exacerbations and Enhance Rehabilitation - Movement Study
This study uses smartwatches to understand how movement affects health for people with conditions like heart disease or diabetes. Researchers hope to find ways to predict health changes and improve wellbeing programmes using the information from the watches.
United Kingdom - RecruitingNA
Early Percutaneous Transluminal Angioplasty in Diabetic Foot Syndrome (PTA-DFS)
This study looks at treating diabetic foot ulcers with a procedure called angioplasty. Researchers want to know if having this treatment quickly makes a bigger difference to healing than having it later. It's about finding the best timing for care.
Germany - AuthorisedTherapeutic use (Phase IV)
Phase IV open-label clinical trial of the immunogenicity and safety of standard dose trivalent inactivated influenza vaccine (Vaxigrip) in a population of people with obesity
This study is looking at how well the standard flu jab (Vaxigrip) works and how safe it is for people who are obese. It will also look at those with type 2 diabetes. We want to see if their bodies make enough protection against the flu after having the vaccine.
Sweden - Recruiting
Precision Subclassification of Mental Health in Diabetes: Digital Twins for Precision Mental Health to Track Subgroups
This study looks at how mental health and diabetes are linked. Researchers want to find different groups of people with diabetes who share similar mental health challenges, so they can offer more personal and effective support.
Germany - RecruitingNA
Diabetes Interventional Assessment of Slimming or Training to Lessen Inconspicuous Cardiovascular Dysfunction
This study looks at how type 2 diabetes affects the heart in younger adults. We're testing if a special diet plan or an exercise programme can improve heart health and reverse fatty changes in the liver and heart, compared to standard care.
United Kingdom - Recruiting
Prognostic Imaging Biomarkers for Diabetic Kidney Disease
This study looks for new ways to spot kidney problems early in people with diabetes. Using special scans like MRI and ultrasound, researchers hope to find early signs of kidney damage before it gets worse, helping doctors give the best care.
Finland · France · Italy - Active not recruitingNA
Pharmacist Case Finding and Intervention for Vascular Prevention Trial
This study looks at how pharmacists can help people lower their risk of heart disease. Heart disease is very common, and pharmacists often see patients. They might be able to help you understand and reduce your personal risk factors for heart problems.
Canada - Not yet recruitingNA
SCORE! Non-Physician Health Worker (NPHW) Implementation Protocol (SIP)
This study helps people in the SCORE! Cohort with high blood pressure, unhealthy cholesterol, or blood sugar issues. We're using trained health workers, not doctors, to support better health through lifestyle advice and check-ups over 12 months.
Canada - Active not recruiting
Is Fat in the Liver a Marker of Post-Pregnancy Glycaemic Deterioration in Women With Gestational Diabetes?
This study looks at whether extra fat in the liver (NAFLD) in women who had gestational diabetes means their blood sugar control might get worse after pregnancy. It uses ultrasound and MRI scans to understand these changes and how they relate to the body's use of insulin.
United Kingdom - Recruiting
Cryopreserved Hair Follicles for Disease and Cell Replacement
This study explores using cells from hair to help treat conditions like diabetes and injuries. Researchers are looking into growing these cells in the lab to create new ways of understanding and treating diseases.
Canada - Recruiting
Development of a Biomarker Panel for the Earlier Prediction of Acute Kidney Injury in Patients With Diabetes
This study looks for early warning signs of kidney problems in people with diabetes undergoing heart procedures. We want to find new ways to predict and prevent kidney damage caused by the dye used in these important tests, aiming to make them safer for more patients.
United Kingdom - RecruitingPHASE3
Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease
This study, called Proact, is investigating a new treatment called REACT (also known as rilparencel) for people with type 2 diabetes and chronic kidney disease. Researchers want to see if this treatment can help kidney function and if it is safe.
United States · Australia · Canada - RecruitingNA
Helping Couples Communicate Better: Does This Help Persons With Type 2 Diabetes Respond Better to a Step Count Prescription?
This study looks at how couples can improve communication to help people with Type 2 Diabetes walk more. Participants will use step counters, set goals, and some will get counselling to help them work together for better health.
Canada - RecruitingNA
The Effect of Time-Restricted Eating in Cardiometabolic Health
This study looks at how eating only within a 9-hour window affects health in people who are overweight and have prediabetes. We want to see if this eating pattern can improve important health markers related to heart and metabolic health, without changing body weight.
United Kingdom - Ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
A research study of a new medicine (NNC0650-0013) in healthy men
This study is looking for healthy men to test a new medicine for the first time. The medicine might help with weight and type 2 diabetes. It's an early-stage study to see how safe it is and how it works in the body.
Germany - Recruiting
Berlin-Brandenburg Pregnancy Cohort
This study looks at how immune cells and placenta cells work together in pregnant women. Researchers want to understand why some women get conditions like pre-eclampsia or diabetes during pregnancy, and how these conditions might affect the mother's heart and blood vessels.
Germany - Recruiting
Investigating the Metabolic and Lipidomic Profiles That Are Associated With Varying Grades of Diabetic Maculopathy and Retinopathy in South Wales
This study in South Wales looks at how diabetes affects your eyes. We're checking blood and urine to understand why some people get worse eye damage. We also check gut bacteria. Our aim is to find new ways to protect your sight.
United Kingdom