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  1. Langerhans' Cell Histiocytosis Professional

    Chemotherapy with cladribine or cytarabine is the most suitable treatment for pituitary/hypothalamic lesions, multifocal brain lesions or any brain lesion in multi-system disease.

  2. Primary Myelosclerosis Professional

    Recombinant erythropoetin and hydroxyurea have been used to treat anaemia. Cladribine is particularly useful post-splenectomy with thrombocytopenia and hepatomegaly. [ 3 ] Thalidomide was ...

  3. Waldenström's Macroglobulinaemia Professional

    Fludarabine + cyclophosphamide + rituximab (FCR). Cladribine + rituximab (Clad-R). Chlorambucil is suitable treatment for elderly frail patients.

  4. Mastocytosis and Mast Cell Disorders Professional

    Aggressive systemic forms of mastocytosis may be treated with interferon alfa, pegylated interferon alpha, corticosteroids, or cladribine. In some cases, more intensive treatments such as ima...

  5. Myelofibrosis Professional

    Post-splenectomy myeloproliferation: cytoreductive therapy (hydroxycarbamide). Cladribine can be considered in selected patients. Anaemia [ 1 ] Red cell transfusions are recomm...

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