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    Psoriatic Arthritis Professional

    Tumour necrosis factor (TNF) inhibitors: TNF inhibitors (adalimumab, etanercept, golimumab and infliximab) should be considered: In patients with active arthritis and an inadequat...

    Chronic Plaque Psoriasis Professional

    Third-line therapy which refers to systemic biological therapies that use molecules designed to block specific molecular steps important in the development of psoriasis, such as the TNF antagonists ad...

    Episcleritis and Scleritis Professional

    Biological response modifiers (BRMs), such as infliximab or adalimumab, may be effective. Other alternatives are golimumab, certolizumab, tocilizumab and rituximab.

    Psoriasis of Hands and Feet (including Palmoplantar Pustulosis) Professional

    Calcineurin inhibitors such as tacrolimus or pimecrolimus and biological agents such as infliximab and alefacept have been used with some success [ 5 ] . Complications Pain can restri...

    Cryptococcosis Professional

    Epidemiology Cryptococcosis is the most common cause of HIV -related meningitis in Central and Southern Africa, accounting for up to 40% of cases. [ 1 ] Pulmonary cryptococcosis is also b...

    Felty's Syndrome Professional

    Various disease-modifying antirheumatic drugs (DMARDs) have been used with mixed success and few data are available on the use of biological agents that might even increase the infection risk. [ 4 ] ...

    Pityriasis Lichenoides Professional

    For the much more serious condition of febrile ulceronecrotic PLEVA: Aggressive treatment with immunosuppressant and/or immunomodulating agents as well as intensive supportive care are recommend...

    Granuloma Annulare Professional

    The TNF inhibitor infliximab - may be useful in recalcitrant cases. [ 5 , 6 ] Adalimumab has also been reported to be effective. [ 7 ] With subcutaneous lesions in children, the best ...

    Febrile Neutrophilic Dermatosis Professional

    Examples include indometacin, colchicine, potassium iodide, dapsone, ciclosporin, doxycycline, metronidazole, isotretinoin, methotrexate, cyclophosphamide, chlorambucil, adalimumab, infliximab...

    Juvenile Idiopathic Arthritis Conditions

    Options include: Etanercept Tocilizumab Infliximab Abatacept Adalimumab What are the complications of juvenile idiopathic arthritis?

    Ulcerative Colitis Conditions

    For example, azathioprine , ciclosporin or infliximab are sometimes needed to control a flare-up of ulcerative colitis. Laxatives Although most people with ulcerative colitis have di...

    Hidradenitis Suppurativa Conditions

    Another similar medicine called infliximab may also be effective, but has not been approved for this use yet in the UK. Other older medicines which affect the immune system which are occasion...

    Uveitis Conditions

    These include medicines called TNF alpha-blockers, such as etanercept and infliximab. Treatment of underlying conditions and causes If there is an underlying cause of your uveitis thi...

    Hidradenitis Suppurativa Professional

    Anti-TNF therapies have been shown to be effective; adalimumab has recently been approved by the National Institute for Health and Care Excellence (NICE) for treating moderate to severe hidradenitis s...

    Hypersensitivity Vasculitis Professional

    Treatments that work via cytokine blockade or lymphocyte depletion, such as tumour alpha inhibitor infliximab and the anti-B-cell antibody rituximab, are showing benefit in certain vasculitic...

    Psoriatic Nail Disease Professional

    A significant improvement was detected in the methotrexate group for the nail matrix findings and in the ciclosporin group for the nail bed findings. [ 5 ] Systemic biological treatments ...

    Behçet's Disease Professional

    TNF antagonists - eg, infliximab - can be effective. Mucocutaneous lesions and joint involvement: These may respond to non-steroidal anti-inflammatory drugs, prednisolone, levam...

    Polyarteritis Nodosa Professional

    In patients with active hepatitis B, antivirals and plasma exchanges prevent the development of long-term hepatic complications of hepatitis B viral infection. [ 17 ] Intravenous immunoglobulin (I...

    Pyoderma Gangrenosum Professional

    Biological therapies (anti-tumour necrosis factor alpha treatments): [ 11 ] Infliximab - some success reported in trials. [ 12 ] ; used in some departments. [ 4 ] Etanercept - succe...

    Toxic Epidermal Necrolysis Professional

    Ciclosporin A. [ 14 ] Tumour necrosis factor (TNF) antagonists - eg, infliximab, etanercept. [ 15 , 16 ] Antibiotics are generally not given prophylactically.