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    Malignant Hyperthermia Professional

    Malignant Hyperthermia, Synonyms: malignant hyperpyrexia, malignant hyperthermia susceptibility, MHS, hyperthermia of anaesthesia, King syndrome, King-Denborough syndrome...

    Neuroleptic Malignant Syndrome Professional

    Neuroleptic Malignant Syndrome, The condition shares many features with the serotonin syndrome and malignant hyperpyrexia. It presents a diagnostic challenge. Epidemiology [ 1 ] ...

    Malignant Skin Ulcers Conditions

    Malignant Skin Ulcers, One cause of a skin ulcer is when a cancerous (malignant) tumour occurs on, or just below, the skin surface. A skin ulcer caused by a cancerous tumour often ha...

    Heat-related Illness Professional

    If there is a history of recent inhalational anaesthetic, consider malignant hyperpyrexia . Recreational drug toxicity, particularly involving cocaine, amfetamines and ecstasy, is an incr...

    Arthrogryposis Multiplex Congenita Professional

    Anaesthesia can be a problem, as some patients with some forms of arthrogryposis are at risk of malignant hyperpyrexia. [ 8 ] Social and psychological care This encompasses some fund...

    Malignant Mesothelioma Professional

    Malignant Mesothelioma, Malignant mesothelioma is an aggressive tumour of mesothelial cells which usually occurs in the pleura (80-90% of all cases) but also at other sites, includ...

    Malignant Melanoma Professional

    Malignant Melanoma, BRAF V600 has been implicated in different mechanisms underlying the development of melanomas. [ 2 ] Malignant melanoma of skin See the separate Malig...

    Important Complications of Anaesthesia Professional

    Idiosyncratic reactions related to specific agents - eg, malignant hyperpyrexia with suxamethonium, succinylcholine-related apnoea. Iatrogenic - eg, pneumothorax related to central line inse...

    General Anaesthesia Professional

    Slow recovery from anaesthetic due to poor cardiac, hepatic or renal function, drug interactions, incorrect drug or dosage and inadequate reversal (uncommon). Malignant hyperpyrexia caused...

    Malignant Melanoma of Skin Professional

    Malignant Melanoma of Skin, See also the separate Malignant Melanoma article. Normal melanocytes are found in the basal layer of the epidermis. , cutaneous malignant ...

    Brain Cancer and Brain Tumours Conditions

    Primary malignant brain tumours A primary malignant brain tumour is a cancer which arises from a cell within the brain.

    Hyperthyroid Crisis (Thyrotoxic Storm) Professional

    Often, there is sudden onset of severe hyperthyroidism with: [ 4 ] Hyperpyrexia (over 41°C), dehydration. Heart rate greater than 140 beats per minute (with or without atrial ...

    Types of Cancer Conditions

    Cancerous (malignant) tumours Malignant tumours tend to grow quite quickly, and invade into nearby tissues and organs, which can cause damage.

    Malaria Conditions

    If the malarial infection becomes established, then malarial symptoms can come in cycles, occurring every 2-3 days (see above). Malignant malaria Malignant malaria is caus...

    Leukoplakia Professional

    The presence of a nodule indicates malignant potential. A lesion that is hard in its periphery is predictive of malignant change.

    Congenital Pigmented Naevus Professional

    The main clinical concern is the development of malignant melanoma . Epidemiology Approximately 1-3% of all newborns have congenital pigmented naevi. [ 2 ] Presentation The naev...

    Sebaceous Naevus Professional

    In later life there may be overgrowth of components of the lesion indicating possible benign or malignant tumours developing within the lesion. Differential diagnosis The appearanc...

    Blue Naevus Professional

    Does not have any malignant potential. Usually a solitary lesion with a predilection for the head (especially the scalp), neck, sacral area and dorsum of the hands/feet.

    Myocarditis Professional

    Physical agents Electric shock Hyperpyrexia Radiation/radiotherapy Investigations ECG: changes may include ST-segment elevation/depression, T-wave inversion, atrial ...

    Drug Abuse - Unusual Presentations Professional

    If suspicious, outline risks and offer immediate referral to secondary care - may need blood cultures, and antibiotics - eg, gentamicin. Hyperpyrexia - consider 'ecstasy'; be wary ...

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