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    Bowel (Colonic) Polyps Professional

    Hamartomatous polyposis syndromes - eg, Peutz-Jeghers' syndrome, juvenile polyposis and Cowden's disease. Peutz-Jeghers syndrome Peutz-Jeghers syndrome is an autos...

    Intussusception in Adults Professional

    Meckel's diverticulum. Peutz-Jeghers syndrome. Familial polyposis coli. Presentation Typically with nonspecific abdominal pain which is recurrent.

    Bowel Polyps (Colonic Polyps) Conditions

    Hereditary nonpolyposis colorectal cancer (HNPCC)/Lynch's syndrome. Gardner's syndrome. Turcot's syndrome. Peutz-Jeghers syndrome. Cowden...

    Causes Diagnosis Treatment

    Intussusception in Children Professional

    Polyps and Peutz-Jeghers syndrome (16%). Henoch-Schönlein purpura (3%). Lymphoma and other tumours (3%).

    Rectal Bleeding in Children Professional

    Examination of the skin may reveal evidence of systemic disorders (for example, Henoch-Schönlein purpura and Peutz-Jeghers syndrome). Examine the abdomen. Look for signs of constipati...

    Screening for the Early Detection of Colorectal Cancer Professional

    Juvenile polyposis - colonoscopy every 18-24 months from the age of 18 (or earlier if there are any symptoms) and upper GI endoscopy every 1-2 years from the age of 25. Peutz-Jeghers syndrome...

    Lentigo Professional

    A number of lentigo-associated conditions can occur: LEOPARD - lentigines, electrocardiographic conduction defects, ocular hypertelorism, pulmonary stenosis, abnormal genitalia, restriction of...

    Bowel Cancer Screening (Colorectal Cancer) Conditions

    Hereditary non-polyposis bowel cancer (HNPCC). Peutz-Jeghers syndrome. Juvenile polyposis syndrome. Close relatives of people with FAP or HNPCC.

    Nail Disorders and Abnormalities Professional

    Black nails These may be a feature of Peutz-Jeghers syndrome, vitamin B12 deficiency, pseudomonas infection and post-irradiation. Black streaks may indicate a junctional melanoc...

    Iron-deficiency Anaemia Professional

    This is the Paterson-Brown-Kelly syndrome (or Plummer-Vinson syndrome) and there is an association with oesophageal carcinoma. Symptoms of severe anaemia (usually not occurri...

    Colorectal Cancer Professional

    Polyposis syndromes: familial adenomatous polyposis (Gardner's syndrome), Turcot's syndrome, attenuated adenomatous polyposis coli, flat adenoma syndrome, hamartomatous polyposis ...

    Pancreatic Exocrine Tumours Professional

    Family history of pancreatic cancer Familial cancer syndromes: BRCA1, BRCA2, familial adenomatous polyposis, Peutz-Jeghers syndrome, familial melanoma syndromes, Lynch syndrome, v...

    Problems in the Mouth Professional

    Other rarer causes include heavy-metal toxicity or Peutz-Jeghers syndrome. Brown or black lesions may be caused by staining from fillings (so-called amalgam tattoo) or naevi (freckles) but...

    History and Physical Examination Professional

    Note the red eye, the freckles on the lips of Peutz-Jeghers syndrome or the white forelock of Waardenberg's syndrome. A number of endocrine disorders may be immediately apparent....

    Neurofibromatosis Professional

    Other conditions with pigmented macules include: Neurocutaneous melanosis. Peutz-Jeghers syndrome . Other localised overgrowth syndromes include: Klippel-Tr...

    Antiphospholipid Syndrome (Hughes' Syndrome) Conditions

    Antiphospholipid Syndrome (Hughes' Syndrome), What is antiphospholipid syndrome? Antiphospholipid syndrome (APS) is sometimes called Hughes' syndro...

    Klinefelter's Syndrome Conditions

    Klinefelter's Syndrome, Klinefelter's syndrome is a genetic condition that only affects males. Affected males have an extra X chromosome. , genetic disorders testosterone...

    Down's Syndrome Conditions

    Down's Syndrome, Mosaic Down's syndrome Mosaic Down's syndrome can also occur. About 2 in 100 people with Down's syndrome have mosaic Down's ...

    Marfan's Syndrome Conditions

    Marfan's Syndrome, Three in four people who have Marfan's syndrome have a parent who also has Marfan's syndrome. You can inherit Marfan's syndrome f...

    Gilbert's Syndrome Conditions

    Gilbert's Syndrome, What is Gilbert's syndrome? Gilbert's syndrome is a condition where the liver does not process bilirubin very well. , gilberts syndrom...

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