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    Hyponatraemia Professional

    Drugs: the most common are thiazide diuretics, selective serotonin reuptake inhibitors (SSRIs), proton pump inhibitors, angiotensin-converting enzyme (ACE) inhibitors and lo...

    Percutaneous Coronary Intervention Professional

    The use of proton pump inhibitors (PPIs) together with clopidogrel (to prevent gastric bleeding) is controversial, after evidence suggesting that PPIs may worsen outcomes and that the two dru...

    Mixed Connective Tissue Disease Professional

    Oesophageal dysfunction may require treatment with proton pump inhibitors. Prostaglandins such as epoprostenol may be used to treat patients who have developed secondary pulmonary hyperten...

    Pulmonary Fibrosis Professional

    Encourage the patient to stop smoking if he or she continues to do so. Proton pump inhibitor therapy should be considered in all and has been associated with stabilisation in lung function...

    Acute Diarrhoea in Adults Professional

    Drugs associated with diarrhoea include allopurinol, antibiotics, digoxin, colchicine, cytotoxic drugs, magnesium-containing antacids, metformin, non-steroidal anti-inflammatory drugs, proton pump...

    Magnesium Disorders Professional

    It has also been found in those with non alcoholic fatty liver. [ 6 ] Patients on long-term proton pump inhibitors (PPIs). There is emerging recognition that long-term PPIs can cause hypo...

    Oesophageal Atresia Professional

    Management is using feed thickeners, H2 receptor antagonists, proton pump inhibitors and prokinetic drugs . [ 2 ] Investigation and anti-reflux surgery are needed in some.

    Oesophageal Strictures, Webs and Rings Professional

    It is characteristically not responsive to proton pump inhibitors (PPIs) [ 2 ] . Extrinsic lesions may compress the oesophagus from outside.

    Multiple Endocrine Neoplasia Type 1 (MEN1) Professional

    The management will depend on the presenting features of each individual patient. [ 3 ] Medical therapy may include diazoxide to inhibit release of insulin (especially in tumours that are not amenable...

    Eosinophilic Oesophagitis Professional

    Originally thought to be a type of gastro-oesophageal reflux disease (GORD), its failure in many (but not all) patients to respond to proton pump inhibitors (PPIs) and the recognition of eosi...

    Helicobacter Pylori Professional

    Either empirical treatment for four weeks with a full-dose proton pump inhibitor (PPI) or testing for and treating H. pylori may be employed. Current evidence offers no guidance on prefe...

    Mallory-Weiss Syndrome Professional

    Haemodynamically unstable patients should have endoscopy immediately after resuscitation. Proton pump inhibitor (PPI) use is not recommended prior to diagnosis by endoscopy. A Cochrane rev...

    Osteoarthritis Professional

    In either case, co-prescribe with a proton pump inhibitor (PPI). All oral NSAIDs/COX-2 inhibitors have analgesic effects of a similar magnitude but vary in their potential gastroi...

    Management of Rheumatoid Arthritis Professional

    NICE recommends prescribing with a suitable proton pump inhibitor (PPI). [ 5 ] NSAIDs improve symptoms and signs of RA. They are highly effective and many RA patients rely on them, but th...

    Stable Angina Professional

    Exercise may aggravate the pain, which is relieved by acid/alginate mixtures and much reduced by a course of a proton pump inhibitor. Pleuritic chest pain: the pain is sharp on deep inspir...

    Chronic Persistent Cough in Adults Professional

    - trial of high-dose proton pump inhibitors (may require up to 12 weeks for improvement). Postnasal drip syndrome?

    Gynaecomastia Professional

    Inhibitors of testosterone action: eg, cyproterone, flutamide, bicalutamide, finasteride, dutasteride, H2 receptor antagonists, proton pump inhibitors (PPIs), marijuana. Androgens causing ...

    Osteoporosis Risk Assessment and Primary Prevention Professional

    Other than aromatase inhibitors and androgen deprivation therapy, other pharmaceutical agents which may increase the risk of fragility fractures include: [ 7 ] : Proton pump inhibitors ...

    Ankylosing Spondylitis Professional

    Drugs No drugs have been shown to modify the course of the disease and there is no evidence to support the use of disease-modifying antirheumatic drugs such as methotrexate or sulfasalazine. [ 7 ] ...

    Prescribing for the Older Patient Professional

    They are best avoided, if possible, for simple pain relief in osteoarthritis (OA), etc; paracetamol should be tried instead and, if this is insufficient, try a low-dose NSAID in addition, with pro...