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    Immune Thrombocytopenia Professional

    Immune Thrombocytopenia, Synonyms: immune thrombocytopenic purpura, ITP The term immune thrombocytopenia (ITP) describes an autoimmune disorder in which the number of circulat...

    Thrombocytopenia and Platelet Function Disorders Professional

    Thrombocytopenia and Platelet Function Disorders, Thrombocytopenia means a reduction in the platelet count below the normal lower limit, which is usually defined as 150 x 10 9 /L. ...

    Grey Platelet Syndrome Professional

    The platelets are large and have a grey appearance on light microscopy. [ 1 ] It is one of the macrothrombocytopenias, which are inherited thrombocytopenias with increased platelet size. [ 2...

    TAR Syndrome Professional

    Synonyms: t hrombocytopenia with a bsent r adius (hence TAR) syndrome, tetraphocomelia-thrombocytopenia syndrome Epidemiology This is a rare autosomal recessive condition. Th...

    Immune Thrombocytopenic Purpura (ITP) Conditions

    What is immune thrombocytopenia? Immune thrombocytopenia (ITP) is an autoimmune disease involving platelets. , anticoagulation blood clotting factor blood coagulation disorder ...

    Bernard-Soulier Syndrome Professional

    Synonyms: giant platelet syndrome This is a congenital bleeding disorder characterised by thrombocytopenia and large platelets. Pathogenesis The molecular defect involves the absence o...

    Wiskott-Aldrich Syndrome Professional

    Autoantibodies may be detected if autoimmune disease is present, especially in autoimmune haemolytic anaemia and immune thrombocytopenia and neutropenia. Consider the diagnosis in boys wit...

    Di Guglielmo's Syndrome Professional

    Erythroleukaemia: characterised by a prominence of myeloblasts in the bone marrow, amegakaryocytic thrombocytopenia and reduced granulopoiesis, leading to neutropenia. Acute myeloid leuka...

    Colorado Tick Fever Professional

    Investigations [ 1 ] Full blood count may show leucopenia and thrombocytopenia . Laboratory testing for the virus will depend on local availability, but the following techniques ...

    HELLP Syndrome Professional

    It is characterised by: Haemolysis (H) Elevated Liver enzymes (EL) Low Platelet count (LP) NB : most isolated cases of thrombocytopenia in pregnancy are due to gestational ...

    Myelodysplastic Syndromes Professional

    Other causes of thrombocytopenia - eg,  immune thrombocytopenia or drugs. Chronic myeloid leukaemia . Bone marrow failure .

    Thrombotic Thrombocytopenic Purpura Professional

    It is characterised by: Microangiopathic haemolysis Thrombocytopenia Neurological abnormalities Fever Renal dysfunction The diagnosis of TTP should be treated as a med...

    Gaucher's Disease Professional

    Presentation [ 6 , 7 ] Type 1 Gaucher's disease May present with chronic fatigue, hepatomegaly, splenomegaly (may become massive), and bone involvement (bone pain due to bone infarcts o...

    Purpuric Rashes Professional

    Excessive platelet destruction such as: Immune problems (eg, immune thrombocytopenia , secondary immune thrombocytopenia - SLE, viral infections, drugs - post-transfusion purpu...

    X-linked Lymphoproliferative Syndrome Professional

    Haematological : atypical mononucleosis (lymphocytosis); thrombocytopenia or bone marrow failure . CNS : meningitis or encephalitis, hepatic encephalopathy .

    Full Blood Count and Blood Smear Conditions

    Too few platelets - this is called thrombocytopenia . This may make you bruise or bleed easily. There are various causes. Too many platelets - this is called thrombocythaemia ( or thro...

    Rubella Professional

    FBC may show a low WBC count with an increased proportion of lymphocytes and thrombocytopenia (usually resolves in a month). Management There is no specific treatment.

    Bone Marrow and Bone Marrow Failure Professional

    Neutropenia - recurrent or severe bacterial infections. Thrombocytopenia - easy bruising, petechiae, bleeding from the nose and/or gums. Presence of hepatomegaly, splenomegaly or ...

    Haemolytic Anaemia Professional

    Autoimmune: Warm antibody type: idiopathic, systemic lupus erythematosus (SLE) , lymphoma, chronic lymphatic leukaemia (CLL) , Evans' syndrome (thrombocytopenia associated with a p...

    Autoimmune Lymphoproliferative Syndrome Professional

    Immune thrombocytopenia. Autoimmune neutropenia - but usually without increased risk of invasive infection, as ALPS patients can mount a neutrophil response to infection.

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