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    Obstetric Cholestasis Professional

    It is characterised by abnormal LFTs (particularly aspartate transaminase (AST) and alanine aminotransferase (ALT) elevation) and an intense pruritus in the absence of skin rash and any other...

    Abnormal Liver Function Tests Conditions

    ALT stands for alanine transaminase and is also called SGPT (serum glutamic-pyruvic transaminase). AST stands for aspartate transaminase and is also called SGOT (serum glutamic ox...

    Eosinophilia-Myalgia Syndrome Professional

    LFTs: elevated levels of bilirubin, alanine transaminase, aspartate transaminase, alkaline phosphatase, and gamma-glutamyltransferase occur in nearly half of all cases.

    Hyperthyroid Crisis (Thyrotoxic Storm) Professional

    Indications of decompensation of homeostasis - eg, renal dysfunction, elevated creatine kinase, electrolyte imbalance (due to dehydration), anaemia, thrombocytopenia, raised white cell count, abnormal...

    Pellagra Professional

    Hepatotoxicity - very rarely, jaundice with a rise in transaminases is seen. Fulminant hepatitis has been reported with very high doses (>3 g per day).

    Babesiosis Professional

    ESR, bilirubin, LDH and transaminases may be elevated. Urine may be dark and urinalysis may show haemoglobinuria and proteinuria. [ 2 ] Immunofluorescence antibody testing or PCR may c...

    Cholestasis Professional

    The history and examination may give some clues as to the likelihood of cholestasis but this can only be confirmed on the basis of LFTs - these will classically show an elevated serum bilirubin in pro...

    Tyrosinaemia Professional

    Serum bilirubin and transaminases are raised with low cholesterol - signifying hepatocellular damage. The alpha-fetoprotein level is raised. , tyrosinaemia type i tyrosinemia type iii...

    Lipid-regulating Drugs (including Statins) Professional

    Statins should not be withheld in patients with high cardiovascular risk who have raised transaminases of no clinical relevance or who have stable hepatic disease - decisions should be made o...

    Abnormal Liver Function Tests Professional

    Further tests to consider Check the other transaminase - in order to ensure you have both ALT and AST results. The ratio of AST to ALT may be useful for distinguishing fatty liver due t...

    Erythema Annulare Centrifugum Professional

    Hyperbilirubinaemia and elevated transaminase levels may be found. Tests for TB, intestinal parasites and a urine test for pregnancy should also be considered if clinically appropriate.

    Parenteral Feeding Professional

    There must be strict adherence to asepsis and solution bags and giving sets must be discarded after 24 hours of use. [ 4 ] Liver and gallbladder dysfunction The majority of patients dev...

    Secondary Liver Cancer Professional

    Bilirubin, alkaline phosphatase and transaminase levels may be raised but LFTs are not always abnormal. A number of tumour markers have been identified, including alpha-fetoprotein (AFP), ...

    Myositis - Polymyositis and Dermatomyositis Professional

    They indicate a poor prognosis with interstitial lung disease. [ 4 ] This lung disease occurs in about a third. [ 5 ] Other enzymes to be elevated include aldolase, serum glutamic-oxaloacetic ...

    Duchenne Muscular Dystrophy Professional

    Increased transaminases (aspartate aminotransferase and alanine aminotransferase, which are produced by muscle as well as liver cells).

    Infectious Mononucleosis Professional

    LFTs: mild elevation of the serum transaminases (higher increases in serum transaminase levels suggest viral hepatitis). Throat swabs: growth of group A streptococci does not iden...

    Hyperlipidaemia Professional

    Renal function: this should be done to exclude chronic kidney disease. LFTs (transaminases): to rule out liver disease in the event of a statin having to be initiated (raised transaminases...

    Relapsing Fever Professional

    LFTs will often show elevation of the transaminases . Elevation of urea and creatinine can occur in louse-borne relapsing fever. During active illness, thick and thin blood films shoul...

    Neuroleptic Malignant Syndrome Professional

    LFTs may show elevated transaminases and lactate dehydrogenase (LDH) of muscle origin. CK is usually elevated. Urine myoglobin should be checked.

    Mycosis Fungoides and Cutaneous T-cell Lymphomas Professional

    Abnormal transaminase values may indicate hepatic involvement. Uric acid: may be raised in aggressive disease.