Does pregabalin cause chronic fatigue

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I was prescribed pregabalin at the beginning of November 2019 for restless legs.

I take 100mg every evening, and it has stopped the RLS. However, since January I have been suffering again with chronic fatigue.

I have a diagnosed history of chronic fatigue going back to the 1990s when I was in my 30s, so know what CFS feels like.

My GP has done all of my bloods - diabetes, liver, kidney, thyroid, iron, Vit D, full blood. All of which have come back normal and the GP is at a loss to what is causing my CFS which is making me physically weak.

Does anyone on this forum know if pregabalin is linked with CFS please?

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  • Edited

    Hi Bagda, I have taken 450mg Pregabalin for general anxiety disorder. Specifically a bewildering illness called depersonalization. I mention that because it is chronic in that I've had little relief in 40 years. However I could sleep all day and it is an effort to self-motivate to try and achieve anything.

    I don't know the symptoms of chronic fatigue but with this drug i am on my way to becoming a sloth.

    Believe me this was very welcome after a lifetime of this terrifying disorder. I feel better all round and believe I should start to rejoin life again. It is my idea to start reducing the drug to achieve some balance. I don't know if this should be any help to you but I will say the amount of sleep I need is becoming a problem. Good luck with your troubles, Alan

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