Hi Mary, so sorry you are having symptoms / reactions, especially not knowing what the "issue" is. There are things you can do to feel better. Everyone is different, but generally when histamine levels are involved (released by mast cells), taking H1 histamine blockers like Zyrtec / Allegra / Claritin / Benadryl and H2 blockers like Zantac clears up minor symptoms. Look for versions without dyes and too many fillers - those often cause more problems.
Find a low histamine food list and choose the lowest histamine foods you can tolerate. No caffeine, alcohol, preservatives, additives, etc. When possible, eat organic whole foods (not processed).
Cook from frozen when possible. Don't cook foods longer than 2 hours (to keep histamine levels low) Freeze leftovers immediately - do not place in the fridge.
Read about common mast cell reaction triggers and avoid as many as possible until you can figure out where your reactions are coming from.
There is an excellent series on the website Mast Attack called "for the practitioner." It's symptoms, what to test for, what the disgnosis types are...
I have MCAD with systemic and GI reactions, although I do get skin reactions on occasion. I see an Immunologist, but other mast cell patients see hemotologists, allergists, endocrinologists, gastroenterologists ... or a combo of several of them.
Tryptase doesn't tell th whole story - mine is considered normal range at 7. My 24 hour methyl-histamine, IGE total and PGD2 were very high. We also tested thyroid (normal) dexascan for bone density (normal) RAST and ImmunoCAP (for allergies - all normal, no allergies)
You have to take control. Most doctors aren't familiar with MCAD yet. Print out literature. Create a full history of all your weird symptoms over the years. ASK to be tested for MCAD. Your GI may be able to re-run you mast cell biopsy to check for KIT mutations (genetic, determines type of mast cell disease).
I know that ^^ was a lot. There are adjustments to make but if you do have a mast cell problem, doing those things above will make a HUGE difference in your symptoms - very quickly, usually 2-3 days.
I hope you find relief soon, and find things that work for you.