Lansoprazole rectal discomfort, bleeding, itching

Posted , 6 users are following.


ive been on Lansoprazole for 2-3 months as I was having mood problems with Omaprazole previously and suffer from GERD. I have found the mood to be vastly improved, however, recently I have been experiencing bleeding when passing stools, and incredibly itchy anus, and severe discomfort when sitting (not like piles). Initial research may suggest that Lansoprazole may cause these symptoms. Has anyone had any similar experience? I'm going to stop taking them, and go back to the Zantac over the counter (which really doesn't hit the spot with the GERD, but relieves the worst of it).

Let me know your experiences with this.


1 like, 5 replies

Report / Delete

5 Replies

  • Posted

    You ned to replace some of the vitamin B12 it drains from you. This affects mood. pp1s reduce nutrition so you have to put that right. Then those symptoms stop. Research it as to which symptoms affect you etc. I had the same ones you mentioned.
    Report / Delete Reply
  • Posted

    Update: I stopped taking  Lansoprazole for 2 weeks, and the previous symptoms disappeared. Obviously the original symptoms of severe acid reflux came back. I then went back onto the Lansoprazole only for the rectal discomfort bleeding and itching to return within a matter of days. I am trying to supplement any lost nutrients, which is clearly having no effect. Does anyone else have any experiences like this? I need something to control the GURD, and have already discounted Omaprazole as this gave me terrible mood swings (again these stopped once I stopped taking them). Ranitidine doesn't touch the GURD. Does anyone have any positives relating to other PPI's, or do I push my GP and private health for some kind of evasive surgery?
    Report / Delete Reply
  • Posted

      My experiences have been pretty much the same.  I had a very itchy anus and light to heavy bleeding after a bowel movement. This started 2 weeks after beginning treatment for GERD with Lansoprazole. I went to my GP but he tried to assure me that it wasn't because of my medication. I took myself off the Lansoprazole and within days all my symptoms  when away.  The GERD returned within a week but I rather live with that than what I was experiencing. I did try one more time just to be sure so after a month I went back on the medication and guess what, it all came back.  I have found that what and when I eat have helped with the GERD symptoms.  Not eating after 5 PM does help me.  No more wine with dinner and small meals all help.


    Report / Delete Reply
  • Posted

    I was on that stuff for a number of years. It destroyed me. I have bone issues now because of it. I was also losing feeling in my leg. That was a side effect. The symptoms subsided somewhat when I stopped. Those pills are near impossible to just quit cold turkey as GERD comes back with a vengence. There is a study out on it. I stopped using them as a result of reading the study. I don't remember most of what it said, but it was nothing good. I'll try to find the name of the study and bring it back here if I can.
    Report / Delete Reply

Join this discussion or start a new one?

New discussion Reply

Report or request deletion

Thanks for your help!

We want the forums to be a useful resource for our users but it is important to remember that the forums are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the forums is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.

newnav-down newnav-up