Long term use of Omeprazole

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Hello,

I am a long term user of this medicine and wanted to share my experience of this medicine and my condition which was diagnosed some 15 years ago.

I was diagnosed with IBS (Irritable Bowel Syndrome), I have for many years suffered with diahorea stomach bloating and general pain and discomfort in my stomach. I have had several endoscopys and various other tests including an ultrasound and at first they discovered nothing unusual and put it all down to IBS. I had several treatments for Helicopacter Pylori and I am still not sure if it ever cleared up. I recently had an operation to remove my gallbladder and gallstones after the acid reflux was very troublesome. I have now since had another endoscopy which has showed I have a hiateul hernia. I have been on Omeprazole for over four years after having acid reflux type symptoms along with my IBS. I wanted to ask about being on this medicine long-term and the possible other organs in my body that could be damaged. I still have very bad indigestion and stomach aches and wondered if these tablets actually work for me anymore

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  • Posted

    I came on this site as I have been taking 20mg Omaprazole ever since I had my gall bladder out 10yrs ago recently I have been suffering with acid reflux so thinking I may have a bigger problem went to the doctors who just told me to double the dose. Having read everyone's comments I'm not as worried as I was but I think I will still get a second opinion to see if there is another problem that the Omaprazole is masking.

    thanks everyone for the information very useful.

  • Posted

    I was taking Omeprazole (Losec) 20 mgs for around 10 years and it was most effective for acid reflux.

    I have had a hiatus hernia from birth and though not over weight, I found that as I got older the symptoms became worse as time went by.

    Following a series of events, my medication was changed to Nexium 40mgs (this is of the same group of drugs but stronger) Both work by preventing the secretion of hydrocholric, stomach acid.

    Incidentally, this does not stop reflux, it merely stops the burning sensation in the Oesophagus thus making it non painful to the patient. Reflux still occurs but damage is still occurring to the Oesophagus and since the introduction of these ppi's (proton pump inhibitors) there has been an increase in cancer rates, thought to be because the patient is less aware of the reflux and subsequently not avoiding foods that increase the reflux in the first place.

    Within 24 hours I was experiencing tinitus and vertigo big time, so much so that I fell onto my hand and sustained a very nasty fracture...this led to a DEXA scan which showed me to have Osteoporosis in my spine ( a spine of someone 30+ years my senior) and my hip, Osteopenia elsewhere. I was horrified and terrified as Id blindly taken medication and not done any in depth research.

    I decided to research and found that it is said that PPI's (Omeprazole and Nexium being two of them) cause the body not to absorb Magnesium and other nutrients/vitamins thus, over time causing the early onset of Osteoporosis. Of course, we have stomach acid for a reason, if we remove it, then it stands to reason that it cannot do its job and subsequently we will suffer the consequences. There have now been some test cases which have been silenced but successful in Courts.

    It occurred to me finally that I had to stop taking this medication and try to find a way of coping without this medication, this turned out to be a complete nightmare.

    I had no issue for 24 hours and then the acid literally flooded by into my stomach and I was in complete agony, even water caused production, I felt that if I didnt take more medication I might die, the pain was excruciating and worse when I tried to lie down and sleep. I had no sleep for several nights.

    It was so difficult to do this, my GP tried to persuade me to start the meds again even intermittently but I refused. Gaviscon was my only friend! I felt as though I had a huge lump in my throat which threatened to occlude my breathing.

    I searched and searched the internet for answers and finally found the blog of a man in Sweden who went through the same as me, it took him ages and then finally he met a Physician who suggested he might have a Lactose intolerance! This was one of those Eureka moments in life for me.

    All my life getting heart burn, I would drink milk to neutralise it and after a short time it would worsen and I would need more milk!

    Lactose eliminated from my diet changed my life, I am now very sensitive to it and if there is a small amount consumed, I am somewhat it agony..bloating, pain, acid, nausea, diarrhoea...a total nightmare!

    It really is essential to know what is causing a problem, so often it is a simple answer like nutrition, something you are sensitive to. Milk is not made for humans, its made to feed a calf to 500kgs!!

    Also, whilst I was taking the Omeprazole, I suffered increasing ill health, my immunity was terrible, I would catch anything going (I lived a healthy outdoor life and ate well, no pre made food)I ended up taking Antibiotics every few weeks and had incessant Chest Infections.

    Since removing this horrible drug from my life, almost 3 years ago, eating healthily, taking purely vitamins, minerals and oils NO medication other than Gaviscon as and when ... I have had no chest infections, no colds, no illness and NO Antibiotics. It takes time for the stomach to settle and it was the most painful experience but thank God I have adopted a very healthy life and now life is worth living.

    I am in the Medical profession and I do not deny the place for Modern medication, however like everything in life, look for the simple answer first. Look for the reason rather than immediately for the easiest solution!

    • Posted

      How long did it take for your stomach to settle?

      How old are you?

      How long did you have the lump in your throat as I have that feeling now?

      And are you gonna be able to reverse the results of your Dexa scan by not taking this medication?

      And how are you doing now with it?

      I have been on PPI's for about 12 years now, I am 34 male and have tried to ween myself off of them but its absolutely Horrible.  (I feel sorry for my wife and 2 kids because it changes my whole outlook on life and attitude when you feel like this and nobody understands unless they have been through the extreme like I have and sounds like you have to.)   I don't drink milk or anything lactose related. I try to eat very healthy along with food combining as well.  I prop myself up at night and do not eat less than 3 hours before bedtime.  I have even considered the procedure where they tie the upper part of your stomach to the lower part of your esouphagus to play the role of the LES.   

      Hope you get this.  

      Thanks in advance for your reply

    • Posted

      Hi Samuel, apologies for the delay.

      It took a few weeks to settle my issues with the excess acid, great pain and even greater determination. I totally understand your situation, its absolutely horrendous. I found that it was dictating my life, my moods and the only respite from it was taking another Omeprazole! The determination has to be paramount here.

      I certainly hope that I can reverse the Dexa scan results though there are no definite promises. I do however feel most strongly that there is NO quick fix to this. I was offered a 6 month injection to build bone density but I refused it, (anything that stays in your system for 6 months sounds scary to me..no reversing that! Also, a very rare fracture of the femur was listed in the small print on the net as a side effect...but it would build up bone density incredibly fast. The two put together spelled instability and brittle bone to me. Now, two years or so later of looking at this drug, the incidence of this fracture is incredibly, frighteningly high) 

      I believe that bone needs to be built slowly and with the correct nutirents and no other way. So, I await to have another scan.

      Through diet and 'thoughtful' living, I feel so healthy and havent had one chest infection or even a cold since in over two years which is incredible seeing I was getting chest infections every fortnight, regular antibiotics etc etc.

      How long did I have the lump feeling in my throat? It was also for a while, possibly a month or so (sorry I dont recall as its a time ago)the 'lump' feeling is I think due to erosion/imflammation of the oesophageal lining, so until youre able to reduce the reflux, it will continue to be irritated.

      Recently I have had some excess stress in my life which led to me eating later, I could feel the 'lump' returning and I was horrified... so, I have returned now to eating no later than 6pm and having little to drink until I get up in the morning.

      I do not eat any animal products, I eat as much organic food as possible, I have found that eating almonds most definitely quashes the acid, which is interesting... I eat masses of fruit (I couldnt eat any before unless I took the dreaded tablets) I drink lemon and water, sometimes apple cider vinegar (first press) and avoid actual sugar. I only eat spelt flour. I cant eat foods with chemicals in them, processed foods or high fat foods.

      It has changed my whole life and also I have lost weight that wouldnt shift before, v slowly but with no adverse effects. Its a pain in some ways being so picky about foods but sincerely, you are what you eat.

      In short, its an horrendous start, the pain with drive you insane esp at night ...but if you can be incredibly strong, chew on the almonds and maybe introduce foods one at a time (try the Paleo diet, its amazing..more about foods,recipes rather than calorie counting), you will feel so much better eventually Im sure.

      As you said, unless you go through it yourself, there is no way of understanding how horrible this is to go through.

      I saw my way through by drinking gallons of Gaviscon which unfortunately contains parabens, I only looked this up a few months ago stupidly... you will need something like this to keep your sanity, the almonds will help and that was a recent discovery too...

      I honesly feel your pain, the thought of going through it again is terrible!! Thinking back, even water gave me pain sad Good luck and if I can help, message me)

    • Posted

      Hi, I was on omezrepole for 10+ years and nexium before that. My brother also suffers from gerd. After trying to stop it I had a severe reflux attack that lasted over 6 hours. He told me about natural ways to help it and he is cured! I slowly weaned off the meds and started taking apple cider vinegar... It works! I take a shot of it in a medicine cup and flush it down with a glass of water. I do this a couple times a day and now mostly just do it when know I will be drinking wine... This was my worst offender! The acids are now balanced. In my stomach so even if I don't do the shot I am OK. It tastes horrible but Better than gerd! It works instantly on attacks too. I was drinking a lot of alcohol and stated feeling heart burn and literally 5 min after a shot of braags apple cider vinegar and a water chase it was calmed. Good luck. That med is making you dependent on it... But it actually hurting you.
    • Posted

      I have read your account with great interest. As an omeprazole user I have also been struggling with iron deficiency and desperately wondering why my iron levels have not gone up. I have had an iron infusion and levels went up. But it is only after some reading that I discover that omeprazole inhibits iron absorption. I am trying to stop the omeprazole but it is incredibly difficult. I am trying all the things which others have recommended on here. Not an easy thing to do. I just hope there is light at the end of the tunnel and I can no longer feel burning in my throat!

       

    • Posted

      I also been on that for over 10 years and I've been having alot of vertigo and muscle ache and back hurts alot and just recently found out I have osteoporosis, do u think I should take to my doctor about it? I tried to not take it for a day and was up all night with acid reflux bad !!!
    • Posted

      Hi Emma2467. I dont know if you eat large amounts in one go, but if so..cut the amounts right down, maybe eat more frequent meals, dont eat after 6, (eat a good while before lying down to sleep) raise the head of your bed around 9 inches and then ensure that for the time youre trying to leave off the Omeprazole, that the foods are non acidic fairly bland.

      There is no easy fix to going through this, sadly when the proton pumps start to work again, they seem to have a party and flood the stomach with acid sad BUT, find out what works best for you in terms of possibly: 1/4 teaspoon bicarbonate soda in some water, Cider apple vinegar in water works for some, I personally find that if I feel the acid coming back now, I chew organic almonds... I think you will most likely need some sort of antacid like Gaviscon to get through these first few days.

      Its a lot of experimentation with foods, finding out what does and doesnt suit you. Ive already said that I now eat no dairy or animal proteins/fats.

      Ive never been so well.

      It might be worth noting also when looking at what youre consuming, some research points to Fluoride added in tap water combines with calcium to a form that the body cant absorb.

      Good luck, sincerely its so worth the effort, I havent even had a cold in 3 years since sorting myself out! smile

    • Posted

      Hi Sharon07754

      Yes, there are many nutrients that are not absorbed with the absence of acid...nutrients that are vital to good health, not only bones but also the whole body!

      Magnesium is essential for muscles... athletes use a lot of magnesium, any extra exertion uses up more, as does stress in your life (some great books out there written by Drs purely about Magnesium..well worth investing in, youll be surprised what insufficiency does to your body)

      I think everyone should report their experiences to their GP definitely.. if you dont tell him, he cant be informed, he will get all his information from Pharmacueticals who produce these drugs and feedback is essential.

      In the end though, you must do your own research on the net, read books and educate yourself sincerely... no one has as much interest in your health as you!

      There are many products on the market as supplements and theyre necessary if you have Osteoporosis or Osteopenia. Try getting a Calcium/Magnesium bone mix with Boron,vitamin D and Vitamin K and other trace elements.

      Try drinking water free from Fluoride also...

      A good diet with nuts, leafy green veggies and fruit also.. Best of luck with getting yourself off this drug, be strong and determined, it does take a while sad

    • Posted

      Hello . Thanks so much for the reply and useful recommendations. I have had no omeprazole for almost two weeks. It is tough and I have had one day where I did not take gaviscon. I have eliminated dairy and a lot of fats and drinking lemon and water. I have two friends my age who take Omeprazole and also I discovered both my neighbours take it too. It seems quite a lot of people are prescribed it. From November to December last year I had a very painful wrist and thumb and this was whilst I was taking two lots of 20mg omeprazole. When I suggested to the doctor that ' could it be a side effect of the omeprazole?' he didn't seem to think so but I was not convinced.

      I Just wanted to ask how it was before you felt no burning?It is a nasty thing. Thanks for the inspiration.

    • Posted

      Hi Emma, I feel your pain..literally!

      It was a few weeks if Im totally honest with you, the soreness from the acid when it flowed back was then difficult, it felt as if I had a lump in my throat for a while, it was only at this point that I discovered that a major part of my problem was dairy.. I discovered a blog from a Swedish man, I was mirroring his experience and he had been to numerous specialists when he eventually found out what his issue was (not forgetting the Hiatus hernia, which I had from birth) 

      Im sure its different for every person but I do believe that nutrition is half our problem as humans, since this time I have studyied nutrition in depth.

      I find that many doctors dismiss the facts out of hand, indoctrinated by the big Pharmas who feed the industry but the tide is changing, there are many lawsuits going on around the world against this drug and winning. I have many colleagues who think I have lost the plot smile

      Its your duty to yourself to keep on top of research and developments, just as it is to make the decision to swallow the pill in the first place.

      You must be patient with yourself, the acid will come back at times, but when you examine what you have eaten/consumed, you will find your way through and know what aggravates your stomach. I find that I cant drink wine now, I thought it was a problem and it definitely is.. for me its like drinking acid! sad

      Im about 3 years on from being off this medication and although it might seem like a long time, it was well worth it..never been so healthy and rarely get any acid issues ..

    • Posted

      Hi Emma, I'm in the same situation. I was diagnosed with acute iron deficiency anaemia  in March last year. My doctor had me jumping through hoops with internalcamera examinations and then decided they would check my bone marrow levels. Imagine my shock when I discovered the link between Omeprazole and iron absorption. Why didn't my doctor know this , I wonder, instead of frightening the life out of me with fears of bowel cancer. I'm going to have a word with my pharmacist about a alternative to Omeprazole as I really have no faith in my doctor! 
    • Posted

      Hi Lettie, yes it is a shock to find out that Omeprazole inhibits absorption of of iron as well as other minerals. I have struggled with iron deficiency for eight years and I have been taking omeprazole for eight years but no GP has told me to stop taking the  omeprazole even when I have struggled to tolerate iron tablets and not been able to take them. I was wondering why the ferritin levels never went up after each blood test.

      I have had no omeprazole for three weeks and will go for a blood test in a few weeks. Another side effect of taking the omeprazole I think was aching in back and wrist, dry skin, difficulty sleeping, more anxiety than usual. Will keep posting here. Good luck with the iron. Are you taking iron tablets?

    • Posted

      This is all great advice and similar to the kind of diet I've been following myself with good results.  I've had all the PPI's with side effects and after researching them discovered how bad they are long term.  Plus they seem to soak up the natural acid in your stomach which causes further discomfort.  Its not easy sticking to a totally healthy diet especially if you like to eat out and I've now lost too much weight which is causing me further concern.  I've found that a bitter herb called centaurium works really well to stop the reflux - taken 5 minutes before eating, as does aloe vera, probiotics, magnesium and omega 3.  Although omega 3 can also cause flare ups in some people.  There's lots of info on the web around trigger foods - just a case of finding your own, I find chocolate, coffee, sparkling wine (in fact anything fizzy) and fried foods are the worst offenders
    • Posted

      Hi. I'm new to this site, but your symptoms really struck a chord with me! Have you ever been tested for COELIAC disease? I was only diagnosed at 54yrs of age, after my daughter was diagnosed. The iron def. is a classic symptom, and my mother was diagnosed at 79 after I made a fuss. It was too late for her. It is a simple blood test and is more common than is realised. If you have it, persuade your family to get tested too as it runs in families. Good luck!

       

    • Posted

      Thank you. I will do that as am still occasionally taking the meds and would like a solution.
    • Posted

      I just wanted to say I am hugely grateful for the post here that you wrote. It helped me so much and gave me inspiration where there was no hop. I do not take omeprazole any longer. I control the acid reflux by diet. I should never have accepted the omeprazole. I was on it for eight years. Coming off it was a nightmare absolutely but I cut out all the things recommended. I have lactose free milk and cheese now and that does seem to help. No alcohol. Many thanks. Good luck to anyone else who wants to stop it too.
    • Posted

      I was interested in your post. I've only been on omeprazole for 1.5 yrs. I was diagnosed with a grade be hiatus hernia via a scope. At first everything was fine, but then I started to get side effects. I didn't realize they were that until I did some research and actually reach the PIB.  After speaking with my physician it turns out I do suffer from clostridium difficile , tremors and difficulty breathing. These are listed in the PIB, but we know the mind can suggest things which is why I spoke to a professional first.

      Because of my reactions, my physician is asking I take myself off the med. He does not want me back on a PPI. He suggested I see a nutritionist.  I decided to look at homeopathic remedies.  I am weaning myself off of the medication and going back to a very old remedy, which has worked well so far: charcoal dissolved in water (a good amount of water). It used to be available as a powder available in most chemists, but I have now found it in pill form. I still recommend the dissolving in water. I can't "stomach" the apple cider remedy.

      Any other suggestions/thoughts are very welcome and appreciated. 

    • Posted

      Hi Samantha, it's very difficult to manage in many ways!

      years on I find that food dictates much of how I feel.. however over time I've spent so many hours researching and reading about nutrition.

      my thoughts have changed recently due to the fact that I think evidence stacks up against calcium supplements and of course all the remedies for acid control contain calcium. 

      I know thatcider apple vinegar sounds horrible but if you make up maybe a tablespoon of the vinegar in two tablespoons of warm water (maybe add a splash of maple syrup to quash the taste (I realise this is sugar but the remedy still works) and take a good sip of this before you eat anything. This works for me, most of the time, not all unfortunately.

      im not a fan of drinking bicarbonate of soda because I believe that the real issue for most people ironically is low stomach acid.

      Getting your diet on track has to be the answer, you'll get to know what you can or can't eat.

      i just cannot eat cake with margarine in it... it's too painful after the event, processed foods with additives also cause pain. Maybe we are the lucky ones in that our bodies are rejecting things that are bad for us? 

      Those who can eat everything although free from pain, are possibly doing untold damage to themselves ... I like to look on the bright side!

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