Oestrogen (estrogen) Shortage in XXY Males
Posted , 3 users are following.
XXY teenagers sometimes grow very tall because they have insufficient oestrogen.
So even if your XXY son is taking testosterone, if it does not increase at a steady rate like it does in XY boys, he may grow to be very tall anyway.
You might not know this but the testes convert some of the testosterone they produce directly themselves into oestrogen. Oestrogen is also produced in fat and in muscle, but the testes do the most converting.
If the testes are diseased they will not produce sufficient testosterone, there will be less conversion to oestrogen, and it is oestrogen that causes the long bones to stop growing. That is why females are generally shorter than males, they have more oestrogen earlier and their epiphyses (the ends of the bones, where they grow from) stop growing.
Females have their growth spurt at the start of puberty and males at the end of puberty, for a very good reason.
It takes time for the testes to produce sufficient testosterone to be converted at sufficient rate to cause boys’ long bones to stop growing. XXY boys are then at risk of growing excessively tall because of a disease in their testes called Seminiferous Tubule Dysgenesis.
It may be appropriate to give XXY boys additional oestrogen as well as testosterone especially if they don’t have much fat or muscle?
Ask your sons’ doctor to think about this.
1 like, 8 replies
XXY XXYGuy
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XXYGuy XXY
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XXY XXYGuy
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XXY XXYGuy
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XXYGuy XXY
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I thought for years that I was diagnsoed late, and I set about having the next generation of XXY's diagnosed a lot earlier. Then when the internet came to fruition it became apparent that I was diagnosed early compared to my same age peers.
The problems experienced by me and others relate to the fact that we look normal, yet fail to relate socially. Once that primary/secondary school period is over the chances of changing anything in the communication/learning areas is virtually nil.
In New Zealand there is no research programmes for anybody, our population is far too small. None of us are considered. But I have influence in many areas of the internet simply by putting information out there, and I expect in time more people will be diagnosed as a result. I have been contacted even by American parents who read my posts, think to themselves 'that sounds like my boy' have him checked, and sure enough he is XXY.
So professional studies are not the only way the next generation can be found.
XXY's are human beings, we pop up in all walks of life. many of us have no difficulties other than infertility. However there is a wide variety of diffuclties that can affect us, how can all those individuals be helped by any research, even research targeted to adults?
In my opinion, the thing that will improve the lives of all adult XXY's is INFORMATION. It is certainly the thing that has improved my life.
XXY XXYGuy
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john03425 XXYGuy
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I always thought it was the lack of testosterone that prevented our bones from fusing.
I know that T gets converted into oestrogen for some of us to a lesser or greater degree and that, curiously women produce T after going through the change of life.
For your interest I am 47,XXY and was diagnosed when I was 37 - I am now 72. Small world, eh?
John 03425
XXYGuy john03425
Posted
Apparently XXY guys have a much greater conversion of testosterone to oestrogen in % than normal males, but since they have insufficient testosterone it makes no difference for most. My father had 'ducks disease' very short legs and a long body. I may have got my leg length genes from him, and late epiphyseal closure because I'm XXY, it turned out I am of normal height. My XY brother is substantially taller than me.
I was diagnosed at 17, treated since I was 18, and I've been diagnosed for 40 years, 5 years longer than you!