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Proton Pump causes joint pain

Posted , 15 users are following.

wiltreath
wiltreath

I have been suffering from severe joint pain for years. Doctors and specialist put this down to arthritis, but they were wrong.  The cause was Omeperazole causing Vitamin B12 deficiency.  It was easily corrected by taking a high dose of Vitamin B12.  Within a week, pains in foot, back, hips, shoulders, and hands have nearly disappeared. Furthermore, swelling in leg has greatly reduced.  Omeprazole has been dumped, and I am back on Losec 10 mg.

1 like, 24 replies

24 Replies

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  • Guest
    Guest wiltreath

    Posted

    I know this is an old thread but I feel I must make comment.  There seems to be some confusion re the dose of PPIs, lets remember that although all PPIs work 'similar' (note I did not say the same you will have to read the papers) they are taken in different doses.  To make it easy I've linked the Nice guidance.   Hope this prevent confusion smile to anyone reading this thread as time proceeds. Also its common knowledge re the B12 and Magnesium levels, you must take supplements of both  as required by blood tests. Or just take them as standard. 

     https://www.nice.org.uk/guidance/cg184/chapter/appendix-a-dosage-information-on-proton-pump-inhibitors

  • marge65643
    marge65643 wiltreath

    Posted

    Also remember to have your iron checked, not just circulating measures such as hemoglobin or iron in a CBC.  Ask for ferritin also.  The storage of iron in the cell seems to be where PPI's have the strongest effect on iron and low levels of total iron as well as low levels of ferritin will cause muscle pain, mostly at the attachment to joints.  This feels a lot like joint pain but it isn't.  I've been on PPI's for over 20 years and dealt with this issue for a long time before my Dr and I figured it out.  Be sure and take the RDA/day for copper (1 to 1.5 mg )and zinc 12 - 15 mg) along with 18 mg of fumerate.  This form of iron seems to work the best with PPI issues.  Marge Garrod, MS PhD

    • wenonah93681
      wenonah93681 marge65643

      Posted

      Marge, I stumbled upon this site desperately looking for help with joint pain and a host of other perplexing symptoms. I now believe these are related to taking PPI's. I have had IV iron infusions in the past. The Dr. I saw was somewhat perplexed by the cause as I now longer menstruate. It now makes sense! I would appreciate any information you could give me to help me continue to take the PPI's. I have a hiatal hernia post failed lap band. I now have abdominal adhesions and would appreciate any help that would allow me to continue to take the PPI's without the side effects to my joints. I have completely eliminated caffeine, sugar, white flour, sleep elevated, etc. The only thing that really does the trick is the omeprazole. I can't imagine not having it. 

  • sansat
    sansat wiltreath

    Posted

    Thx for the comments all.  I went to see the general doctor and he has request a full blood check (iron/B12 etc etc).  But I had a flu when I went to see him so he asked to delay the blood tests until I feel better else the results will be off.

    Doctors here in the UK are too quick to give the medication without our future health in mind.  No one told me about regular blood tests to check for vitamin levels, but the NHS in the UK would probably not do that for us anyway.  I read the leaflet but because the symptoms came on slowly I did not think it was to do with the omeprazole.  I discussed with the doctor that I wanted to stop the Omeprazole full stop,  He said I could but needed to replace with something else at the same time (he suggested ZanTac).  So I have been off it totally now for 4 days (not sure when any rebound will kick in).  I will report back if there are any improvements.

    Thanks.

    • marge65643
      marge65643 sansat

      Posted

      Most Drs don't check ferritin when they ck iron, just hemoglobin and iron.  That's not good enough.  CHeck and see if that is on your orders and if not ask your Dr.  It's cheap and your Dr shouldn't have a problem ordering it.

       

    • Guest
      Guest sansat

      Posted

      To right, as long as your in and out as fast as possible they're happy.  To be honest I've tried and tried to come off of PPIs and back onto H2 but cant.  Oh well.  Anyway here's a link to tests re vitamin and minerals whilst taking PPIs.  I never knew anything about vit C!!!  Have a read:

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110863/

  • dave333
    dave333 wiltreath

    Posted

    I know this is an old thread but never the less here goes. I wont go into the details of how long, what does etc etc I'm on. PPIs are a godsend but like all other meds they have negative effects also. I had joint pain and found that 900mg/day Magnesium worked. I tested this by coming off/on several times and each time it worked for me. I also take 2000ug B12/day but it was the mag that worked for me.

  • michael911
    michael911 wiltreath

    Posted

    magnesium wouldnt hurt either! im also taking b12 for the same reasons.

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