Alteplase, dornase alfa clinical trials

The Fourth Multicentre Intrapleural Sepsis Trial (MIST-4) - a randomised clinical randomised effectiveness study comparing early video assisted thoracic surgery and early intrapleural enzyme therapy in adult patients with pleural infection

This study compares two treatments for lung infection: enzyme therapy and keyhole surgery. Both aim to clear fluid around the lungs. This trial will help doctors understand which treatment works best, ensuring patients get the most effective care for this serious condition.