- CompletedPhase II
A Phase II study of axitinib in patients with metastatic renal cell cancer unsuitable for nephrectomy
This clinical trial looks at a targeted drug called axitinib for people with advanced kidney cancer. It is designed for adults whose cancer has spread and who cannot have surgery to remove their kidney. Researchers want to see how well axitinib works to shrink tumours or slow cancer growth.
For: Renal cancerUnited Kingdom · England - Active not recruitingPHASE3
Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing
This study offers continued access to treatments like Avelumab for people who were in earlier Pfizer studies and are still benefiting. It focuses on several cancers and ensures ongoing care and tracking of their health.
For: Advanced Malignancies · NSCLC · Ovarian CancerUnited States · Australia · Belgium - CompletedPhase II
A study to see how effective the drug Axitinib is at preventing cancer cells from growing and to see if this means that patients with kidney cancer require less extensive surgery
This study tests whether a targeted cancer medicine called axitinib can shrink kidney cancer that has grown into nearby large veins. Researchers want to see if taking this drug before surgery makes the operation safer, smaller, and easier for doctors to perform.
For: Clear cell renal cell cancer with venous thrombus invasionUnited Kingdom · England · Scotland - Active not recruitingPHASE1
A Study to Evaluate MEDI5752 and Axitinib in Subjects With Advanced Renal Cell Carcinoma
This study looks at new drug combinations for advanced kidney cancer. We want to see how safe and effective MEDI5752 is when given with either Lenvatinib or Axitinib to people with this type of cancer.
For: Advanced Renal Cell CarcinomaUnited States · Australia · France - Active not recruitingPHASE2
A Study of Immune Checkpoint Inhibitor Combinations With Axitinib in Participants With Untreated Locally Advanced Unresectable or Metastatic Renal Cell Carcinoma
This study looks at new drug combinations for kidney cancer that has spread or can't be removed. It compares different immune-boosting medicines with a drug called axitinib to see how safe and effective they are.
For: Renal Cell CarcinomaUnited States · Australia · China