BiDil, Placebo (to Hydralazine / Isosorbide dinitrate), Placebo (To Metformin hydrochloride), METFORMIN HYDROCHLORIDE clinical trials

Hydralazine-ISDN in Patients With Chronic Heart Failure - Hydralazine Heart Failure Trial (H-HeFT) Metformin in Patients with Chronic Heart Failure and Diabetes or Insulin Resistance - Metformin Heart Failure Trial (Met-HeFT) A randomized, 2 x 2 factorial designed, double-blind, placebo controlled study (DANHEART).

This study looks at two different treatments, BiDil and Metformin, for people with long-term heart failure. Researchers want to see if these treatments can reduce serious events like hospital stays, heart transplants, or heart attacks, and improve overall health.