- Active not recruitingPHASE3
Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia
This study looks at a new way to treat a type of leukaemia (blood cancer) called B-cell precursor acute lymphoblastic leukaemia (ALL) in older adults. It compares a drug called Blinatumomab combined with gentler chemotherapy against the usual chemotherapy treatment to see which works best.
For: Newly Diagnosed Philadelphia (Ph)-Negative B-cell Precursor Acute Lymphoblastic Leukemia (ALL)United States · Australia · Austria - RecruitingPHASE3
A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia
This study, called ALLTogether, is for children and young adults aged 0-45 with acute lymphoblastic leukaemia (ALL). It aims to improve survival and reduce side effects by combining the best treatments from several countries and testing new approaches.
For: Leukemia, Acute LymphoblasticBelgium · Denmark · Estonia - RecruitingPHASE3
Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017
This study looks at new ways to treat childhood leukaemia (ALL) in children and teenagers. It aims to make treatments kinder and more effective by using smart medicines (immunotherapy) and targeting specific cancer features, reducing the need for harsh chemotherapy.
For: Acute Lymphoblastic Leukemia, PediatricAustralia · Austria · Czechia - RecruitingPHASE3
Interfant-21 Treatment Protocol for Infants Under 1 Year With KMT2A-rearranged ALL or Mixed Phenotype Acute Leukemia
This study looks at a new drug called blinatumomab for babies under one year old with a specific type of leukaemia (blood cancer). The aim is to make treatments better for these tiny patients by adding blinatumomab to their usual care. It's a key step in finding more effective ways to fight this illness.
For: Acute Lymphoblastic Leukemia · Mixed Phenotype Acute LeukemiaArgentina · Australia · Austria - Not yet recruitingPHASE3
International Study for Treatment of Childhood Relapsed Precursor B-Cell ALL 2020 (IntReALL BCP 2020)
This study is looking at new ways to treat a type of childhood leukaemia called B-Cell Acute Lymphoblastic Leukaemia (ALL) when it comes back. It aims to use kinder, more targeted treatments instead of strong chemotherapy.
For: B-Cell Acute Lymphoblastic LeukaemiaAustria · Belgium · Czechia - Not yet recruitingPHASE2, PHASE3
Framework for Optimizing, Refining, and Unifying Management of HSCT in Pediatric ALL
This study looks at new ways to make stem cell transplants safer and more effective for children and young people with a type of blood cancer called ALL. Researchers want to reduce serious side effects and improve long-term health for these patients.
For: Acute Lymphoblastic Leukemia (ALL) · Stem Cell Transplant · Graft -Versus-host-diseaseAustria · Czechia · Denmark - RecruitingPHASE2
A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases
This study looks at new treatments (inebilizumab and blinatumomab) for people with Systemic Lupus Erythematosus (SLE) and Rheumatoid Arthritis (RA). It mainly checks how safe these medicines are and if they help reduce symptoms of these conditions.
For: Systemic Lupus Erythematosus · Active Refractory Rheumatoid ArthritisUnited States · Australia · Belgium