- RecruitingPHASE2
Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer
This study looks at adding a new drug, relatlimab, to current treatments for nasopharyngeal cancer that has come back or spread. The aim is to see if this addition can help keep the cancer from growing or spreading for longer.
For: Metastatic Nasopharyngeal Carcinoma · Recurrent Nasopharyngeal Carcinoma · Stage IV Nasopharyngeal Carcinoma AJCC v8United States · Australia · Canada - Active not recruitingPHASE2
Testing the Addition of the Drug Relugolix to the Usual Radiation Therapy for Advanced-Stage Prostate Cancer, The NRG Promethean Study
This study looks at combining a drug called relugolix with usual radiation therapy for advanced prostate cancer that has spread to limited other areas. It aims to see if this combination helps stop the cancer from spreading further compared to radiation alone.
For: Oligometastatic Prostate Carcinoma · Prostate Adenocarcinoma · Prostate Ductal AdenocarcinomaUnited States · Canada - RecruitingNA
Contribution of MUltiparametric Analysis in Bone Scintigraphy for the Characterisation of Solitary Bone Lesions
This study looks at a special type of bone scan, called SPECT-CT, to help doctors understand solitary bone lesions. It aims to see if this scan can accurately tell which lesions are harmless so patients can avoid unnecessary biopsies and their risks.
For: Bone LesionFrance - RecruitingPHASE3
Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma
This study looks at the best way to treat a rare childhood lung cancer called Pleuropulmonary Blastoma (PPB). For Type I PPB, it compares surgery alone to surgery with chemotherapy. For Types II and III PPB, it adds a new drug, Topotecan, to standard treatment.
For: Pleuropulmonary BlastomaUnited States · Canada - Active not recruitingPHASE3
A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk Rhabdomyosarcoma
This study looks at new ways to treat a type of cancer called rhabdomyosarcoma, which can be aggressive. We're testing if adding a drug called vinorelbine to standard treatment, and then using a 'maintenance' therapy, helps stop the cancer from coming back.
For: Alveolar Rhabdomyosarcoma · Botryoid-Type Embryonal Rhabdomyosarcoma · Embryonal RhabdomyosarcomaUnited States · Australia · Canada - RecruitingPHASE3
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
This study compares two ways to give radiation therapy for high-risk prostate cancer. One uses fewer, stronger treatments (SBRT), and the other is the usual longer course. We want to see if the shorter treatment works just as well to stop the cancer from coming back.
For: Prostate Adenocarcinoma · Stage III Prostate Cancer AJCC v8 · Stage IVA Prostate Cancer AJCC v8United States · Canada · Hong Kong - RecruitingPHASE3
Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma
This study is giving children and young adults with a type of soft tissue cancer called rhabdomyosarcoma new chemotherapy. It aims to see if less harsh treatment works for those with very low-risk cancer, and if standard treatment works well for others, while also studying patients with specific genetic changes.
For: Embryonal Rhabdomyosarcoma · Fusion-Negative Alveolar Rhabdomyosarcoma · Spindle Cell/Sclerosing RhabdomyosarcomaUnited States · Australia · Canada - RecruitingNA
SPECT/CT Bone Scan Quantification Surgery
This study looks at a special type of bone scan (SPECT/CT) before back surgery for ongoing pain. Researchers want to see if this scan can predict which patients will get the most relief from the surgery, called lumbar arthrodesis.
For: Pseudoarthrosis of BoneFrance - RecruitingPHASE2
Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery
This study looks at new ways to treat a rare type of skin cancer called mucosal melanoma, found inside the body. It tests if a drug called nivolumab, alone or with another drug called cabozantinib, can stop the cancer from coming back after surgery or help those where surgery wasn't enough.
For: Anal Melanoma · Bladder Melanoma · Cervical MelanomaUnited States · Canada