- RecruitingPHASE3
Study of Olverembatinib (HQP1351) in Patients With CML-CP
This study is looking at a new medicine called olverembatinib for people with a type of blood cancer called Chronic Myeloid Leukemia (CML-CP). It compares olverembatinib with an existing medicine, bosutinib, and also checks the new medicine for those with a specific gene change (T315I mutation).
For: Chronic Myeloid Leukemia · CML · CML, Chronic PhaseUnited States · Australia · Belgium - Active not recruitingPHASE1, PHASE2
Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia
This study is testing a new medicine called Bosutinib for children and teenagers (1-17 years old) with a type of blood cancer called Philadelphia chromosome-positive Chronic Myeloid Leukemia (CML). It aims to find the right dose and see how safe and effective it is.
For: Philadelphia Chromosome Positive CML · Accelerated Phase Chronic Myelogenous Leukemia · Blastic Phase Chronic Myelogenous LeukemiaUnited States · France · Germany - Active not recruitingPHASE3
A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP
This study looks at a new medicine called asciminib for adults with a type of blood cancer called CML. Researchers want to see if it works better than other standard CML treatments. It's for people recently diagnosed who haven't had treatment yet.
For: Chronic Myeloid Leukemia (CML) Philadelphia Chromosome PositiveUnited States · Australia · Austria - RecruitingPHASE4
Asciminib Roll-over Study
This study is for people who have already been taking a medicine called asciminib (or similar drugs) in a Novartis study for a type of blood cancer called CML. It allows them to keep taking the medicine if their doctor thinks it's still helping them.
For: Chronic Myelogenous Leukemia · Leukemia, Myelogenous, Chronic, BCR-ABL PositiveUnited States · Argentina · Austria